EIF3C anticorps (C-Term)

N° du produit ABIN2854357

Cet anticorps Lapin Polyclonal détecte spécifiquement EIF3C dans WB. Il présente une réactivité envers Humain.

Aperçu rapide pour EIF3C anticorps (C-Term) (ABIN2854357)

Antigène: EIF3C (Eukaryotic Translation Initiation Factor 3 Subunit C (EIF3C))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EIF3C est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-EIF3C anticorps

Épitope: C-Term

Réactivité croisée: Humain

Attributs du produit: Rabbit Polyclonal antibody to eIF3 p110 (eukaryotic translation initiation factor 3, subunit C)
eIF3 p110 antibody [C2C3], C-term

Purification: Purified by antigen-affinity chromatography.

Immunogène: Recombinant protein encompassing a sequence within the C-terminus region of human EIF3S8. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Commentaires:

Positive Control: 293T

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.9 mg/mL

Buffer: 1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.01 % Thimerosal

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Détails sur EIF3C

Antigène: EIF3C (Eukaryotic Translation Initiation Factor 3 Subunit C (EIF3C))

Autre désignation: eukaryotic translation initiation factor 3 subunit C

Sujet: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of posttermination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.

Cellular Localization: Cytoplasm

Poids moléculaire: 105 kDa

ID gène: 8663

UniProt: Q99613

Pathways: Ribonucleoprotein Complex Subunit Organization