Tryptophan Hydroxylase 2 anticorps
Aperçu rapide pour Tryptophan Hydroxylase 2 anticorps (ABIN2854368)
Antigène
Voir toutes Tryptophan Hydroxylase 2 (TPH2) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Réactivité croisée
- Humain, Souris, Rat, Poisson zèbre (Danio rerio)
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Attributs du produit
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Rabbit Polyclonal antibody to TPH2 (tryptophan hydroxylase 2)
TPH2 antibody [N3C3] -
Purification
- Purified by antigen-affinity chromatography.
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Immunogène
- Recombinant protein encompassing a sequence within the center region of human TPH2. The exact sequence is proprietary.
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Isotype
- IgG
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Indications d'application
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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Commentaires
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Positive Control: mouse hippocampus , mouse midbrain
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1.3 mg/mL
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Buffer
- 1XPBS pH 7, 20 % Glycerol, 0.025 % ProClin 300
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Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- Tryptophan Hydroxylase 2 (TPH2)
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Autre désignation
- tryptophan hydroxylase 2
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Sujet
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This gene encodes a member of the pterin-dependent aromatic acid hydroxylase family. The encoded protein catalyzes the first and rate limiting step in the biosynthesis of serotonin, an important hormone and neurotransmitter. The human genome contains two related tryptophan hydroxylases, one on chromosome 11p15-p14 and one on chromosome 12q21. This gene is expressed predominantly in the brain stem. Mutations in this gene may be associated with psychiatric diseases such as bipolar affective disorder and major depression.
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Poids moléculaire
- 56 kDa
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ID gène
- 121278
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UniProt
- Q8IWU9
Antigène
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