TADA3L anticorps (C-Term)

N° du produit ABIN2854371

Cet anticorps anti-TADA3L est un anticorps Lapin Polyclonal détectant TADA3L dans WB. Adapté pour Humain.

Aperçu rapide pour TADA3L anticorps (C-Term) (ABIN2854371)

Antigène: TADA3L (TADA3) (Transcriptional Adaptor 3 (TADA3))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TADA3L est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-TADA3L anticorps

Épitope: C-Term

Réactivité croisée: Humain

Attributs du produit: Rabbit polyclonal antibody to TADA3L (transcriptional adaptor 3 (NGG1 homolog, yeast)-like)
TADA3L antibody [C1C3]

Purification: Affinity purified by Protein A.

Immunogène: Recombinant protein encompassing a sequence within the C-terminus region of human TADA3L. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Commentaires:

Positive Control: TADA3L transfected 293T

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 9.46 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Détails sur TADA3L

Antigène: TADA3L (TADA3) (Transcriptional Adaptor 3 (TADA3))

Autre désignation: transcriptional adaptor 3

Sujet: Many DNA-binding transcriptional activator proteins enhance the initiation rate of RNA polymerase II-mediated gene transcription by interacting functionally with the general transcription machinery bound at the basal promoter. Adaptor proteins are usually required for this activation, possibly to acetylate and destabilize nucleosomes, thereby relieving chromatin constraints at the promoter. The protein encoded by this gene is a transcriptional activator adaptor and has been found to be part of the PCAF histone acetylase complex. In addition, it associates with the tumor suppressor protein p53 and is required for full activity of p53 and p53-mediated apoptosis. At least four alternatively spliced variants have been found for this gene, but the full-length nature of some variants has not been determined.

Cellular Localization: Nucleus

Poids moléculaire: 49 kDa

ID gène: 10474

UniProt: O75528

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway