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Proteasome 26S S3 (Center) anticorps

Cet anticorps anti- est un anticorps Lapin Polyclonal détectant dans WB, ICC et IF. Adapté pour Humain.
N° du produit ABIN2854383

Aperçu rapide pour Proteasome 26S S3 (Center) anticorps (ABIN2854383)

Antigène

Proteasome 26S S3

Reactivité

  • 1
  • 1
Humain

Hôte

  • 1
Lapin

Clonalité

  • 1
Polyclonal

Conjugué

  • 1
Inconjugué

Application

Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)
  • Épitope

    Center

     Réactivité croisée

    Macaque rhésus, Chimpanzé, Boeuf (Vache)

    Réactivité croisée (Details)

    Rhesus Monkey (100 %), Chimpanzee (100 %), Bovine (100 %)

    Attributs du produit

    Rabbit Polyclonal antibody to Proteasome 26S S3 (proteasome (prosome, macropain) 26S subunit, non-ATPase, 3)
    Proteasome 26S S3 antibody [C1C3]

    Purification

    Purified by antigen-affinity chromatography.

    Immunogène

    Recombinant protein encompassing a sequence within the center region of human Proteasome 26S S3. The exact sequence is proprietary.

    Isotype

    IgG
  • Indications d'application

    Suggested dilution Reference ICC/IF 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* Western blot1:500-1:3000*

    Commentaires

    Positive Control: 293T , A431 , H1299 , HeLa , HepG2 , Molt-4 , Raji

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    0.97 mg/mL

    Buffer

    0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

    Agent conservateur

    Thimerosal (Merthiolate)

    Précaution d'utilisation

    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    -20 °C

    Stockage commentaire

    Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Antigène

    Proteasome 26S S3

    Sujet

    The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the non-ATPase subunits of the 19S regulator lid.

    Poids moléculaire

    61 kDa

    ID gène

    5709
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