Calpain 3 anticorps (C-Term)
Aperçu rapide pour Calpain 3 anticorps (C-Term) (ABIN2854395)
Antigène
Voir toutes Calpain 3 (CAPN3) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- C-Term
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Réactivité croisée
- Humain
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Attributs du produit
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Rabbit polyclonal antibody to Calpain 3 (calpain 3, (p94))
Calpain 3 antibody [C2C3], C-term -
Purification
- Affinity purified by Protein A.
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Immunogène
- Recombinant protein encompassing a sequence within the C-terminus region of human Calpain 3. The exact sequence is proprietary.
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Isotype
- IgG
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Indications d'application
- WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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Commentaires
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Positive Control: HeLa
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 2 mg/mL
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Buffer
- 1XPBS ( pH 7), 40 % Glycerol, 0.01 % Thimerosal
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Agent conservateur
- Thimerosal (Merthiolate)
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Précaution d'utilisation
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- Calpain 3 (CAPN3)
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Autre désignation
- calpain 3
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Sujet
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Calpain, a heterodimer consisting of a large and a small subunit, is a major intracellular protease, although its function has not been well established. This gene encodes a muscle-specific member of the calpain large subunit family that specifically binds to titin. Mutations in this gene are associated with limb-girdle muscular dystrophies type 2A. Alternate promoters and alternative splicing result in multiple transcript variants encoding different isoforms and some variants are ubiquitously expressed.
Cellular Localization: Cytoplasm -
Poids moléculaire
- 94 kDa
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ID gène
- 825
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UniProt
- P20807
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Pathways
- Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
Antigène
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