Cytohesin 1 anticorps
Aperçu rapide pour Cytohesin 1 anticorps (ABIN2854407)
Antigène
Voir toutes Cytohesin 1 (CYTH1) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Réactivité croisée
- Humain, Poisson zèbre (Danio rerio)
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Attributs du produit
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Rabbit polyclonal antibody to PSCD1 (pleckstrin homology, Sec7 and coiled-coil domains 1)
PSCD1 antibody [N1C1] -
Purification
- Purified by antigen-affinity chromatography.
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Immunogène
- Recombinant protein encompassing a sequence within the center region of human Cytohesin 1. The exact sequence is proprietary.
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Isotype
- IgG
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Indications d'application
- WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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Commentaires
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Positive Control: PSCD1 transfected 293T
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.87 mg/mL
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Buffer
- 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
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Agent conservateur
- Thimerosal (Merthiolate)
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Précaution d'utilisation
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- Cytohesin 1 (CYTH1)
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Autre désignation
- cytohesin 1
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Sujet
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The protein encoded by this gene is a member of the PSCD family. Members of this family have identical structural organization that consists of an N-terminal coiled-coil motif, a central Sec7 domain, and a C-terminal pleckstrin homology (PH) domain. The coiled-coil motif is involved in homodimerization, the Sec7 domain contains guanine-nucleotide exchange protein (GEP) activity, and the PH domain interacts with phospholipids and is responsible for association of PSCDs with membranes. Members of this family appear to mediate the regulation of protein sorting and membrane trafficking. This gene is highly expressed in natural killer and peripheral T cells, and regulates the adhesiveness of integrins at the plasma membrane of lymphocytes. The encoded protein is 83 % homologous to that of CYTH2.
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Poids moléculaire
- 46 kDa
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ID gène
- 9267
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UniProt
- Q15438
Antigène
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