ALAS2 anticorps (Center)

N° du produit ABIN2854459

Cet anticorps Lapin Polyclonal détecte spécifiquement ALAS2 dans WB. Il présente une réactivité envers Humain et Souris et a été mentionné dans 1 publication.

Aperçu rapide pour ALAS2 anticorps (Center) (ABIN2854459)

Antigène: ALAS2 (Aminolevulinate, delta-, Synthase 2 (ALAS2))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ALAS2 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-ALAS2 anticorps

Épitope: Center

Réactivité croisée: Rat (Rattus), Xenopus laevis, Poisson zèbre (Danio rerio), Boeuf (Vache), Xenopus tropicalis

Réactivité croisée (Details): Rat (95 %), Xenopus laevis (81 %), Zebrafish (80 %), Bovine (95 %), Xenopus tropicalis (81 %)

Attributs du produit: Rabbit Polyclonal antibody to ALAS-E (aminolevulinate, delta-, synthase 2)
ALAS-E antibody [N3C3]

Purification: Purified by antigen-affinity chromatography.

Immunogène: Recombinant protein encompassing a sequence within the center region of human ALAS-E. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: Suggested dilution Reference Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceWestern blot1:500-1:3000*

Commentaires:

Positive Control: Raji , K562 , HL60 , mouse liver

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Références pour anticorps anti-ALAS2 (ABIN2854459)

Vercellotti, Khan, Nguyen, Chen, Bruzzone, Bechtel, Brown, Nath, Steer, Hebbel, Belcher: "H-ferritin ferroxidase induces cytoprotective pathways and inhibits microvascular stasis in transgenic sickle mice." dans: Frontiers in pharmacology, Vol. 5, pp. 79, (2014) (PubMed).

Détails sur ALAS2

Antigène: ALAS2 (Aminolevulinate, delta-, Synthase 2 (ALAS2))

Autre désignation: ALAS-E

Sujet: The product of this gene specifies an erythroid-specific mitochondrially located enzyme. The encoded protein catalyzes the first step in the heme biosynthetic pathway. Defects in this gene cause X-linked pyridoxine-responsive sideroblastic anemia. Alternatively spliced transcript variants encoding different isoforms have been identified.

Cellular Localization: Mitochondrion matrix

Poids moléculaire: 65 kDa

ID gène: 212

Pathways: Transition Metal Ion Homeostasis