FBXW2 anticorps (C-Term)
Aperçu rapide pour FBXW2 anticorps (C-Term) (ABIN2854490)
Antigène
Voir toutes FBXW2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Épitope
- C-Term
-
Réactivité croisée
- Humain
-
Attributs du produit
-
Rabbit polyclonal antibody to FBXW2 (F-box and WD repeat domain containing 2)
FBXW2 antibody -
Purification
- Purified by antigen-affinity chromatography.
-
Immunogène
- Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human FBXW2. The exact sequence is proprietary.
-
Isotype
- IgG
-
-
-
-
Indications d'application
- WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
-
Commentaires
-
Positive Control: A431
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Concentration
- 1 mg/mL
-
Buffer
- 1XPBS ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
-
Agent conservateur
- Thimerosal (Merthiolate)
-
Précaution d'utilisation
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Stock
- 4 °C,-20 °C
-
Stockage commentaire
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
-
-
- FBXW2 (F-Box and WD Repeat Domain Containing 2 (FBXW2))
-
Autre désignation
- F-box and WD repeat domain containing 2
-
Sujet
-
F-box proteins are an expanding family of eukaryotic proteins characterized by an approximately 40 amino acid motif, the F box. Some F-box proteins have been shown to be critical for the ubiquitin-mediated degradation of cellular regulatory proteins. In fact, F-box proteins are one of the four subunits of ubiquitin protein ligases, called SCFs. SCF ligases bring ubiquitin conjugating enzymes to substrates that are specifically recruited by the different F-box proteins. Mammalian F-box proteins are classified into three groups based on the presence of either WD-40 repeats, leucine-rich repeats, or the presence or absence of other protein-protein interacting domains. This gene encodes the second identified member of the F-box gene family and contains multiple WD-40 repeats.
-
Poids moléculaire
- 52 kDa
-
ID gène
- 26190
-
UniProt
- Q9UKT8
Antigène
-