METTL3 anticorps
Aperçu rapide pour METTL3 anticorps (ABIN2854497)
Antigène
Voir toutes METTL3 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Réactivité croisée
- Humain, Rat
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Attributs du produit
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Rabbit polyclonal antibody to METTL3 (methyltransferase like 3)
METTL3 antibody [N2C2], Internal -
Purification
- Purified by antigen-affinity chromatography.
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Immunogène
- Recombinant protein encompassing a sequence within the center region of human METTL3. The exact sequence is proprietary.
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Isotype
- IgG
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Indications d'application
- WB: 1:5000-1:20000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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Commentaires
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Positive Control: Molt-4
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
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Agent conservateur
- Thimerosal (Merthiolate)
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Précaution d'utilisation
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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: "METTL3 serves an oncogenic role in human ovarian cancer cells partially via the AKT signaling pathway." dans: Oncology letters, Vol. 19, Issue 4, pp. 3197-3204, (2020) (PubMed).
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: "METTL3 serves an oncogenic role in human ovarian cancer cells partially via the AKT signaling pathway." dans: Oncology letters, Vol. 19, Issue 4, pp. 3197-3204, (2020) (PubMed).
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- METTL3 (Methyltransferase Like 3 (METTL3))
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Autre désignation
- methyltransferase like 3
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Sujet
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This gene encodes the 70 kDa subunit of MT-A which is part of N6-adenosine-methyltransferase. This enzyme is involved in the posttranscriptional methylation of internal adenosine residues in eukaryotic mRNAs, forming N6-methyladenosine.
Cellular Localization: Nucleus speckle -
Poids moléculaire
- 64 kDa
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ID gène
- 56339
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UniProt
- Q86U44
Antigène
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