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METTL3 anticorps

Cet anticorps anti-METTL3 est un anticorps Lapin Polyclonal détectant METTL3 dans WB et IHC (p). Adapté pour Humain. Ce Primary Antibody a été cité dans 1 publication.
N° du produit ABIN2854497

Aperçu rapide pour METTL3 anticorps (ABIN2854497)

Antigène

Voir toutes METTL3 Anticorps
METTL3 (Methyltransferase Like 3 (METTL3))

Reactivité

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Humain

Hôte

  • 42
  • 2
Lapin

Clonalité

  • 40
  • 4
Polyclonal

Conjugué

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Cet anticorp METTL3 est non-conjugé

Application

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  •  Réactivité croisée

    Humain, Rat

    Attributs du produit

    Rabbit polyclonal antibody to METTL3 (methyltransferase like 3)
    METTL3 antibody [N2C2], Internal

    Purification

    Purified by antigen-affinity chromatography.

    Immunogène

    Recombinant protein encompassing a sequence within the center region of human METTL3. The exact sequence is proprietary.

    Isotype

    IgG
  • Indications d'application

    WB: 1:5000-1:20000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    Commentaires

    Positive Control: Molt-4

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 mg/mL

    Buffer

    0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

    Agent conservateur

    Thimerosal (Merthiolate)

    Précaution d'utilisation

    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    4 °C,-20 °C

    Stockage commentaire

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Liang, Guan, Lin, Li, Geng, Li: "METTL3 serves an oncogenic role in human ovarian cancer cells partially via the AKT signaling pathway." dans: Oncology letters, Vol. 19, Issue 4, pp. 3197-3204, (2020) (PubMed).

  • Antigène

    METTL3 (Methyltransferase Like 3 (METTL3))

    Autre désignation

    methyltransferase like 3

    Sujet

    This gene encodes the 70 kDa subunit of MT-A which is part of N6-adenosine-methyltransferase. This enzyme is involved in the posttranscriptional methylation of internal adenosine residues in eukaryotic mRNAs, forming N6-methyladenosine.

    Cellular Localization: Nucleus speckle

    Poids moléculaire

    64 kDa

    ID gène

    56339

    UniProt

    Q86U44
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