LGI1 anticorps

N° du produit ABIN2854526

L’anticorps Lapin Polyclonal anti-LGI1 a été validé pour WB, IF et ICC. Il convient pour détecter LGI1 dans des échantillons de Humain.

Aperçu rapide pour LGI1 anticorps (ABIN2854526)

Antigène: LGI1 (Leucine-Rich, Glioma Inactivated 1 (LGI1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LGI1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

Détail du produit anti-LGI1 anticorps

Réactivité croisée: Humain, Rat

Attributs du produit: Rabbit polyclonal antibody to LGI1 (leucine-rich, glioma inactivated 1)
LGI1 antibody [N2C2], Internal

Purification: Purified by antigen-affinity chromatography.

Immunogène: Recombinant protein encompassing a sequence within the center region of human LGI1. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:10000. ICC/IF: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Commentaires:

Positive Control: A431 , U87-MG , SK-N-SH , SK-N-AS , rat brain

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Détails sur LGI1

Antigène: LGI1 (Leucine-Rich, Glioma Inactivated 1 (LGI1))

Autre désignation: leucine rich glioma inactivated 1

Sujet: This gene is rearranged as a result of translocations in glioblastoma cell lines. The protein contains a hydrophobic segment representing a putative transmembrane domain with the amino terminus located outside the cell. It also contains leucine-rich repeats with conserved cysteine-rich flanking sequences. This gene is predominantly expressed in neural tissues and its expression is reduced in low grade brain tumors and significantly reduced or absent in malignant gliomas. Mutations in this gene result in autosomal dominant lateral temporal epilepsy.

Cellular Localization: Secreted

Poids moléculaire: 64 kDa

ID gène: 9211

UniProt: O95970