STX1A anticorps (N-Term)

N° du produit ABIN2854559

L’anticorps Lapin Polyclonal anti-STX1A a été validé pour WB, IF et ICC. Il convient pour détecter STX1A dans des échantillons de Humain.

Aperçu rapide pour STX1A anticorps (N-Term) (ABIN2854559)

Antigène: STX1A (Syntaxin 1A (Brain) (STX1A))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp STX1A est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

Détail du produit anti-STX1A anticorps

Épitope: N-Term

Réactivité croisée: Humain, Rat

Attributs du produit: Rabbit polyclonal antibody to syntaxin 1A (syntaxin 1A (brain))
Syntaxin 1a antibody [N1], N-term

Purification: Affinity purified by Protein A.

Immunogène: Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human Syntaxin 1a. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Commentaires:

Positive Control: A431

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 9.3 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Détails sur STX1A

Antigène: STX1A (Syntaxin 1A (Brain) (STX1A))

Autre désignation: syntaxin 1A

Sujet: Synaptic vesicles store neurotransmitters that are released during calcium-regulated exocytosis. The specificity of neurotransmitter release requires the localization of both synaptic vesicles and calcium channels to the presynaptic active zone. Syntaxins function in this vesicle fusion process. Syntaxins also serve as a substrate for botulinum neurotoxin type C, a metalloprotease that blocks exocytosis and has high affinity for a molecular complex that includes the alpha-latrotoxin receptor (MIM 600565) which produces explosive exocytosis (Zhang et al., 1995 [PubMed 7622072]).[supplied by OMIM]

Cellular Localization: Cell membrane, Single-pass type IV membrane protein , Isoform 2: Secreted

Poids moléculaire: 33 kDa

ID gène: 6804

UniProt: Q16623

Pathways: Peptide Hormone Metabolism, Synaptic Membrane, Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport