SEC13 anticorps (Center)

N° du produit ABIN2854912

Détail du produit anti-SEC13 anticorps

Antigène: SEC13 (SEC13 Homolog (SEC13))

Épitope: Center

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SEC13 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Réactivité croisée: Souris, Rat (Rattus), Xenopus laevis, Poisson zèbre (Danio rerio), Boeuf (Vache), Xenopus tropicalis

Réactivité croisée (Details): Mouse (97 %), Rat (97 %), Xenopus laevis (88 %), Zebrafish (87 %), Bovine (96 %), Xenopus tropicalis (89 %)

Attributs du produit: Rabbit Polyclonal antibody to SEC13L1 (SEC13 homolog (S. cerevisiae))
SEC13L1 antibody [N1C3]

Purification: Purified by antigen-affinity chromatography.

Immunogène: Recombinant protein encompassing a sequence within the center region of human SEC13L1. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: Suggested dilution Reference ICC/IF 1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Immunoprecipitation 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Immunoprecipitation1:100-1:1000* Western blot1:500-1:3000*

Commentaires:

Positive Control: 293T , A431 , H1299 , HeLa , HepG2 , Molt-4 , Raji

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Références pour anticorps anti-SEC13 (ABIN2854912)

Wolfson, Chantranupong, Wyant, Gu, Orozco, Shen, Condon, Petri, Kedir, Scaria, Abu-Remaileh, Frankel, Sabatini: "KICSTOR recruits GATOR1 to the lysosome and is necessary for nutrients to regulate mTORC1." dans: Nature, Vol. 543, Issue 7645, pp. 438-442, (2017) (PubMed).

Détails sur SEC13

Antigène: SEC13 (SEC13 Homolog (SEC13))

Autre désignation: SEC13L1 (SEC13 Produits)

Synonymes: anticorps D3S1231E, anticorps SEC13L1, anticorps SEC13R, anticorps npp-20, anticorps 1110003H02Rik, anticorps Sec13l1, anticorps Sec13r, anticorps Protein SEC13 homolog, anticorps SEC13 homolog, nuclear pore and COPII coat complex component, anticorps npp-20, anticorps SEC13, anticorps Sec13

Sujet: The protein encoded by this gene belongs to the SEC13 family of WD-repeat proteins. It is a constituent of the endoplasmic reticulum and the nuclear pore complex. It has similarity to the yeast SEC13 protein, which is required for vesicle biogenesis from endoplasmic reticulum during the transport of proteins. Multiple alternatively spliced transcript variants have been found.

Poids moléculaire: 36 kDa

ID gène: 6396