DLD anticorps

N° du produit ABIN2854985

L’anticorps Lapin Polyclonal anti-DLD a été validé pour WB, IF, ICC et IHC (p). Il convient pour détecter DLD dans des échantillons de Humain. Il y a 1 publication disponible.

Aperçu rapide pour DLD anticorps (ABIN2854985)

Antigène: DLD (Dihydrolipoamide Dehydrogenase (DLD))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DLD est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Classe de qualité: KO Validated

Détail du produit anti-DLD anticorps

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Rabbit Polyclonal antibody to DLD (dihydrolipoamide dehydrogenase)
DLD antibody

Purification: Affinity purified by Protein A.

Immunogène: Recombinant protein encompassing a sequence within the center region of human DLD. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Commentaires:

Positive Control: Mouse brain , 293T , PC-12 , Rat2 , HeLa

Validation: KO/KD

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1XPBS ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Références pour anticorps anti-DLD (ABIN2854985)

Shin, Lee, You, Kim, Roh: "Dihydrolipoamide dehydrogenase regulates cystine deprivation-induced ferroptosis in head and neck cancer." dans: Redox biology, Vol. 30, pp. 101418, (2020) (PubMed).

Détails sur DLD

Antigène: DLD (Dihydrolipoamide Dehydrogenase (DLD))

Autre désignation: dihydrolipoamide dehydrogenase

Sujet: This gene encodes the L protein of the mitochondrial glycine cleavage system. The L protein, also named dihydrolipoamide dehydrogenase, is also a component of the pyruvate dehydrogenase complex, the alpha-ketoglutarate dehydrogenase complex, and the branched-chain alpha-keto acide dehydrogenase complex. Mutations in this gene have been identified in patients with E3-deficient maple syrup urine disease and lipoamide dehydrogenase deficiency.

Cellular Localization: Mitochondrion matrix

Poids moléculaire: 54 kDa

ID gène: 1738

UniProt: P09622

Pathways: Ribonucleoside Biosynthetic Process, Cell RedoxHomeostasis