ATRX anticorps (C-Term)

N° du produit ABIN2855005

Cet anticorps Lapin Polyclonal détecte spécifiquement ATRX dans WB, IF, IHC (p), ICC et IP. Il présente une réactivité envers Humain et Souris.

Aperçu rapide pour ATRX anticorps (C-Term) (ABIN2855005)

Antigène: ATRX (helicase 2, X-linked (ATRX))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ATRX est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunoprecipitation (IP)

Détail du produit anti-ATRX anticorps

Épitope: C-Term

Réactivité croisée: Chimpanzé

Réactivité croisée (Details): Chimpanzee (100 %)

Attributs du produit: Rabbit Polyclonal antibody to ATRX (alpha thalassemia/mental retardation syndrome X-linked (RAD54 homolog, S. cerevisiae))
ATRX antibody [C3], C-term

Purification: Purified by antigen-affinity chromatography.

Immunogène: Recombinant protein encompassing a sequence within the C-terminus region of human ATRX. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: Suggested dilution Reference ICC/IF 1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Immunoprecipitation 1:100-1:500* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Immunoprecipitation1:100-1:500* Western blot1:500-1:3000*

Commentaires:

Positive Control: 293T , A431 , HeLa , HepG2 , NIH3T3

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 2.67 mg/mL

Buffer: 1XPBS, 20 % Glycerol ( pH 7). 0.025 % ProClin 300 was added as a preservative.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Détails sur ATRX

Antigène: ATRX (helicase 2, X-linked (ATRX))

Autre désignation: ATRX

Sujet: The protein encoded by this gene contains an ATPase/helicase domain, and thus it belongs to the SWI/SNF family of chromatin remodeling proteins. The mutations of this gene are associated with an X-linked mental retardation (XLMR) syndrome most often accompanied by alpha-thalassemia (ATRX) syndrome. These mutations have been shown to cause diverse changes in the pattern of DNA methylation, which may provide a link between chromatin remodeling, DNA methylation, and gene expression in developmental processes. This protein is found to undergo cell cycle-dependent phosphorylation, which regulates its nuclear matrix and chromatin association, and suggests its involvement in the gene regulation at interphase and chromosomal segregation in mitosis. Multiple alternatively spliced transcript variants encoding distinct isoforms have been reported.

Poids moléculaire: 283 kDa

ID gène: 546