GP120 anticorps

N° du produit ABIN285511

Cet anticorps Chèvre Polyclonal détecte spécifiquement GP120 dans ELISA, WB et IHC. Il présente une réactivité avec des échantillons de Human Immunodeficiency Virus (HIV). Il a été cité dans 4+ publications.

Aperçu rapide pour GP120 anticorps (ABIN285511)

Antigène: GP120 (HIV-1 gp120) (Human Immunodeficiency Virus 1 Surface Glycoprotein (HIV-1 gp120))

Reactivité: Human Immunodeficiency Virus (HIV)

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp GP120 est non-conjugé

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-GP120 anticorps

Purification: purified

Pureté: > 95 % pure

Immunogène: HIV1 gp120 antibody was raised in goat using purified native gp120 from strain IIIB as the immunogen.

Information d'application

Indications d'application: Optimal conditions should be determined byt he investigator.

Restrictions: For Research Use only

Stockage

Concentration: Lot specific

Buffer: Protein A purified IgG fraction in 10 mM PBS, pH 7.2 with 0.1 % NaN3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C for short term storage. Aliquot and store at -20 °C for long term storage.

Références pour anticorps anti-GP120 (ABIN285511)

Ikeda, Symeonides, Albin, Li, Thali, Harris: "HIV-1 adaptation studies reveal a novel Env-mediated homeostasis mechanism for evading lethal hypermutation by APOBEC3G." dans: PLoS pathogens, Vol. 14, Issue 4, pp. e1007010, (2018) (PubMed).

Usami, Wu, Göttlinger: "SERINC3 and SERINC5 restrict HIV-1 infectivity and are counteracted by Nef." dans: Nature, Vol. 526, Issue 7572, pp. 218-23, (2016) (PubMed).

Kondo, Melikyan: "Intercellular adhesion molecule 1 promotes HIV-1 attachment but not fusion to target cells." dans: PLoS ONE, Vol. 7, Issue 9, pp. e44827, (2013) (PubMed).

Miyauchi, Curran, Long, Kondo, Iwamoto, Engelman, Matsuda: "The membrane-spanning domain of gp41 plays a critical role in intracellular trafficking of the HIV envelope protein." dans: Retrovirology, Vol. 7, pp. 95, (2010) (PubMed).

Détails sur GP120

Antigène: GP120 (HIV-1 gp120) (Human Immunodeficiency Virus 1 Surface Glycoprotein (HIV-1 gp120))

Autre désignation: HIV1 Gp120

Classe de substances: Viral Protein

Sujet: Envelope glycoprotein GP120 (or gp120) is a glycoprotein exposed on the surface of the HIV envelope. The 120 in its name comes from its molecular weight of 120 kilodaltons. gp120 is essential for virus entry into cells as it plays a vital role in seeking out specific cell surface receptors for entry.