ACTC1 anticorps

N° du produit ABIN2855212

Cet anticorps Lapin Polyclonal détecte spécifiquement ACTC1 dans WB, ICC, IHC (p) et IF. Il présente une réactivité envers Humain et a été mentionné dans 4+ publications.

Aperçu rapide pour ACTC1 anticorps (ABIN2855212)

Antigène: ACTC1 (Actin, Alpha, Cardiac Muscle 1 (ACTC1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ACTC1 est non-conjugé

Application: Western Blotting (WB), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Détail du produit anti-ACTC1 anticorps

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Rabbit Polyclonal antibody to alpha Cardiac Muscle Actin (actin, alpha, cardiac muscle 1)
alpha Cardiac Muscle Actin antibody

Purification: Purified by antigen-affinity chromatography.

Immunogène: Recombinant protein encompassing a sequence within the center region of human alpha Cardiac Muscle Actin. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:10000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Commentaires:

Positive Control: PC-12 , Rat2 , Jurkat , Raji , K562 , THP-1 , NIH-3T3 , JC , BCL-1 , Rat muscle

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.56 mg/mL

Buffer: 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Références pour anticorps anti-ACTC1 (ABIN2855212)

Henry, Szabó, Sutus, Pirity: "RYBP is important for cardiac progenitor cell development and sarcomere formation." dans: PLoS ONE, Vol. 15, Issue 7, pp. e0235922, (2020) (PubMed).

Oldershaw, Owens, Sutherland, Linney, Liddle, Magana, Lash, Gill, Richardson, Meeson: "Human Cardiac-Mesenchymal Stem Cell-Like Cells, a Novel Cell Population with Therapeutic Potential." dans: Stem cells and development, Vol. 28, Issue 9, pp. 593-607, (2020) (PubMed).

Miksiunas, Rucinskas, Janusauskas, Labeit, Bironaite: "Histone Deacetylase Inhibitor Suberoylanilide Hydroxamic Acid Improves Energetic Status and Cardiomyogenic Differentiation of Human Dilated Myocardium-Derived Primary Mesenchymal Cells." dans: International journal of molecular sciences, Vol. 21, Issue 14, (2020) (PubMed).

Robertson, Wen, Yin, Chen, Smith, Paine: "Multiple Calcium Export Exchangers and Pumps Are a Prominent Feature of Enamel Organ Cells." dans: Frontiers in physiology, Vol. 8, pp. 336, (2017) (PubMed).

Détails sur ACTC1

Antigène: ACTC1 (Actin, Alpha, Cardiac Muscle 1 (ACTC1))

Autre désignation: actin alpha cardiac muscle 1

Sujet: Actins are highly conserved proteins that are involved in various types of cell motility. Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of a two-stranded helix. Each actin can bind to four others. The protein encoded by this gene belongs to the actin family which is comprised of three main groups of actin isoforms, alpha, beta, and gamma. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. Defects in this gene have been associated with idiopathic dilated cardiomyopathy (IDC) and familial hypertrophic cardiomyopathy (FHC).

Cellular Localization: Cytoplasm , cytoskeleton

Poids moléculaire: 42 kDa

ID gène: 70

UniProt: P68032

Pathways: Myometrial Relaxation and Contraction