Prohibitin 2 anticorps

N° du produit ABIN2855290

Cet anticorps Lapin Polyclonal détecte spécifiquement Prohibitin 2 dans WB, IHC (p), IF et ICC. Il présente une réactivité envers Humain.

Aperçu rapide pour Prohibitin 2 anticorps (ABIN2855290)

Antigène: Prohibitin 2 (PHB2)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Prohibitin 2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Immunocytochemistry (ICC)

Détail du produit anti-Prohibitin 2 anticorps

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Rabbit Polyclonal antibody to Prohibitin 2 (prohibitin 2)
Prohibitin 2 antibody

Purification: Purified by antigen-affinity chromatography.

Immunogène: Recombinant protein encompassing a sequence within the center region of human Prohibitin 2. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Commentaires:

Positive Control: Mouse brain , H1299 , HeLa

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.66 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Détails sur Prohibitin 2

Antigène: Prohibitin 2 (PHB2)

Autre désignation: prohibitin 2

Sujet: Acts as a mediator of transcriptional repression by nuclear hormone receptors via recruitment of histone deacetylases (By similarity). Functions as an estrogen receptor (ER)-selective coregulator that potentiates the inhibitory activities of antiestrogens and represses the activity of estrogens. Competes with NCOA1 for modulation of ER transcriptional activity. Probably involved in regulating mitochondrial respiration activity and in aging.

Cellular Localization: Mitochondrion inner membrane (By similarity) , Cytoplasm (By similarity) , Nucleus (By similarity)

Poids moléculaire: 33 kDa

ID gène: 11331

UniProt: Q99623

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling