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Prohibitin 2 anticorps

PHB2 Reactivité: Humain WB, IHC (p), IF, ICC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2855290
  • Antigène Voir toutes Prohibitin 2 (PHB2) Anticorps
    Prohibitin 2 (PHB2)
    Reactivité
    • 74
    • 39
    • 13
    • 11
    • 8
    • 8
    • 7
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 72
    • 2
    • 2
    Lapin
    Clonalité
    • 72
    • 4
    Polyclonal
    Conjugué
    • 46
    • 4
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp Prohibitin 2 est non-conjugé
    Application
    • 65
    • 27
    • 22
    • 18
    • 15
    • 13
    • 13
    • 10
    • 10
    • 8
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Immunocytochemistry (ICC)
     Réactivité croisée
    Humain, Souris, Rat
    Attributs du produit
    Rabbit Polyclonal antibody to Prohibitin 2 (prohibitin 2)
    Prohibitin 2 antibody
    Purification
    Purified by antigen-affinity chromatography.
    Immunogène
    Recombinant protein encompassing a sequence within the center region of human Prohibitin 2. The exact sequence is proprietary.
    Isotype
    IgG
  • Indications d'application
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Commentaires

    Positive Control: Mouse brain , H1299 , HeLa

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.66 mg/mL
    Buffer
    0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
    Agent conservateur
    Thimerosal (Merthiolate)
    Précaution d'utilisation
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Antigène
    Prohibitin 2 (PHB2)
    Autre désignation
    prohibitin 2 (PHB2 Produits)
    Synonymes
    anticorps bcap37, anticorps zgc:73150, anticorps wu:fc28c08, anticorps PHB2, anticorps phb2, anticorps ATPHB2, anticorps F21M11.21, anticorps F21M11_21, anticorps prohibitin 2, anticorps DKFZp469N1310, anticorps BAP, anticorps BCAP37, anticorps Bap37, anticorps PNAS-141, anticorps REA, anticorps p22, anticorps bap37, anticorps prohibitin2, anticorps xphb2, anticorps AU044498, anticorps Bcap37, anticorps Bap, anticorps Bap-37, anticorps Bcap27, anticorps prohibitin 2a, anticorps prohibitin 2, anticorps prohibitin 2 S homeolog, anticorps phb2a, anticorps PHB2, anticorps phb2, anticorps phb2.S, anticorps Phb2
    Sujet
    Acts as a mediator of transcriptional repression by nuclear hormone receptors via recruitment of histone deacetylases (By similarity). Functions as an estrogen receptor (ER)-selective coregulator that potentiates the inhibitory activities of antiestrogens and represses the activity of estrogens. Competes with NCOA1 for modulation of ER transcriptional activity. Probably involved in regulating mitochondrial respiration activity and in aging.

    Cellular Localization: Mitochondrion inner membrane (By similarity) , Cytoplasm (By similarity) , Nucleus (By similarity)
    Poids moléculaire
    33 kDa
    ID gène
    11331
    UniProt
    Q99623
    Pathways
    Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling
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