BAG3 anticorps (C-Term)

N° du produit ABIN2855382

Cet anticorps anti-BAG3 est un anticorps Lapin Polyclonal détectant BAG3 dans WB et IHC (p). Adapté pour Humain.

Aperçu rapide pour BAG3 anticorps (C-Term) (ABIN2855382)

Antigène: BAG3 (BCL2-Associated Athanogene 3 (BAG3))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BAG3 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-BAG3 anticorps

Épitope: C-Term

Réactivité croisée: Humain, Souris

Attributs du produit: Rabbit Polyclonal antibody to BAG3 (BCL2-associated athanogene 3)
BAG3 antibody

Purification: Purified by antigen-affinity chromatography.

Immunogène: Recombinant protein encompassing a sequence within the C-terminus region of human BAG3. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Commentaires:

Positive Control: mouse heart

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.41 mg/mL

Buffer: 1XPBS ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Détails sur BAG3

Antigène: BAG3 (BCL2-Associated Athanogene 3 (BAG3))

Autre désignation: BCL2 associated athanogene 3

Sujet: BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The protein encoded by this gene contains a WW domain in the N-terminal region and a BAG domain in the C-terminal region. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner.

Poids moléculaire: 62 kDa

ID gène: 9531

UniProt: O95817