Desmoglein 2 anticorps (N-Term)

N° du produit ABIN2855411

L’anticorps Lapin Polyclonal anti-Desmoglein 2 a été validé pour WB, IF, ICC et IHC (p). Il convient pour détecter Desmoglein 2 dans des échantillons de Humain.

Aperçu rapide pour Desmoglein 2 anticorps (N-Term) (ABIN2855411)

Antigène: Desmoglein 2 (DSG2)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Desmoglein 2 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-Desmoglein 2 anticorps

Épitope: N-Term

Réactivité croisée: Humain, Souris

Attributs du produit: Rabbit Polyclonal antibody to Desmoglein 2 (desmoglein-2)
Desmoglein 2 antibody [N1N2], N-term

Purification: Purified by antigen-affinity chromatography.

Immunogène: Recombinant protein encompassing a sequence within the N-terminus region of human Desmoglein 2. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Commentaires:

Validation: Orthogonal

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.36 mg/mL

Buffer: 1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.025 % ProClin 300

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Détails sur Desmoglein 2

Antigène: Desmoglein 2 (DSG2)

Autre désignation: desmoglein 2

Sujet: Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. This gene product is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. This second family member is expressed in colon, colon carcinoma, and other simple and stratified epithelial-derived cell lines. Mutations in this gene have been associated with arrhythmogenic right ventricular dysplasia, familial, 10.

Cellular Localization: Cell membrane , Cell junction , desmosome

Poids moléculaire: 122 kDa

ID gène: 1829

UniProt: Q14126

Pathways: Cell-Cell Junction Organization