NFE2 anticorps (Center)
Aperçu rapide pour NFE2 anticorps (Center) (ABIN2855460)
Antigène
Voir toutes NFE2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Center
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Réactivité croisée
- Singe, Porc
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Réactivité croisée (Details)
- Monkey (97 %), Pig (91 %)
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Attributs du produit
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Rabbit Polyclonal antibody to NF-E2 (nuclear factor (erythroid-derived 2), 45 kDa)
NF-E2 antibody [N1C3] -
Purification
- Purified by antigen-affinity chromatography.
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Immunogène
- Recombinant protein encompassing a sequence within the center region of human NF-E2. The exact sequence is proprietary.
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Isotype
- IgG
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Indications d'application
- Suggested dilution Reference ICC/IF 1:100-1:1000* Immunoprecipitation Assay-dependent dilution Western blot 1:500-1:3000* ChIP-sequencing Assay-dependent dilution Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* ImmunoprecipitationAssay-dependent dilution Western blot1:500-1:3000* ChIP-sequencingAssay-dependent dilution
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Commentaires
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Positive Control: 293T , mouse spleen
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1.03 mg/mL
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Buffer
- 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
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Agent conservateur
- Thimerosal (Merthiolate)
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Précaution d'utilisation
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- NFE2 (Nuclear Factor (Erythroid-Derived 2), 45kDa (NFE2))
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Autre désignation
- NF-E2
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Sujet
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Component of the NF-E2 complex essential for regulating erythroid and megakaryocytic maturation and differentiation. Binds to the hypersensitive site 2 (HS2) of the beta-globin control region (LCR). This subunit (NFE2) recognizes the TCAT/C sequence of the AP-1-like core palindrome present in a number of erythroid and megakaryocytic gene promoters. Requires MAFK or other small MAF proteins for binding to the NF-E2 motif. May play a role in all aspects of hemoglobin production from globin and heme synthesis to procurement of iron.
Cellular Localization: Nucleus -
Poids moléculaire
- 41 kDa
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ID gène
- 4778
Antigène
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