DCK anticorps
Aperçu rapide pour DCK anticorps (ABIN2855484)
Antigène
Voir toutes DCK AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Classe de qualité
-
-
Réactivité croisée
- Humain, Souris, Rat
-
Attributs du produit
-
Rabbit Polyclonal antibody to DCK (deoxycytidine kinase)
DCK antibody -
Purification
- Purified by antigen-affinity chromatography.
-
Immunogène
- Recombinant protein encompassing a sequence within the center region of human DCK. The exact sequence is proprietary.
-
Isotype
- IgG
-
-
-
-
Indications d'application
- WB: 1:1000-1:20000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
-
Commentaires
-
Positive Control: PC-12 , Rat2 , A549 , H1299 , 293T , DCK-transfected 293T
Validation: KO/KD, Overexpression
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Concentration
- 1.41 mg/mL
-
Buffer
- 1XPBS pH 7, 20 % Glycerol, 0.025 % ProClin 300
-
Agent conservateur
- ProClin
-
Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Stock
- 4 °C,-20 °C
-
Stockage commentaire
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
-
-
- DCK (Deoxycytidine Kinase (DCK))
-
Autre désignation
- deoxycytidine kinase
-
Sujet
-
Deoxycytidine kinase (DCK) is required for the phosphorylation of several deoxyribonucleosides and their nucleoside analogs. Deficiency of DCK is associated with resistance to antiviral and anticancer chemotherapeutic agents. Conversely, increased deoxycytidine kinase activity is associated with increased activation of these compounds to cytotoxic nucleoside triphosphate derivatives. DCK is clinically important because of its relationship to drug resistance and sensitivity.
Cellular Localization: Nucleus -
Poids moléculaire
- 31 kDa
-
ID gène
- 1633
-
UniProt
- P27707
Antigène
-