PDE4B anticorps (C-Term)

N° du produit ABIN2855498

L’anticorps Lapin Polyclonal anti-PDE4B a été validé pour WB. Il convient pour détecter PDE4B dans des échantillons de Humain.

Aperçu rapide pour PDE4B anticorps (C-Term) (ABIN2855498)

Antigène: PDE4B (phosphodiesterase 4B, cAMP-Specific (PDE4B))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PDE4B est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-PDE4B anticorps

Épitope: C-Term

Réactivité croisée: Humain

Attributs du produit: Rabbit Polyclonal antibody to PDE4B (phosphodiesterase 4B, cAMP-specific)
PDE4B antibody

Purification: Purified by antigen-affinity chromatography.

Immunogène: Recombinant protein encompassing a sequence within the C-terminus region of human PDE4B. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Commentaires:

Positive Control: NT2D1 , PC-3 , HCT116

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.72 mg/mL

Buffer: 1XPBS ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Détails sur PDE4B

Antigène: PDE4B (phosphodiesterase 4B, cAMP-Specific (PDE4B))

Autre désignation: phosphodiesterase 4B

Sujet: This gene is a member of the type IV, cyclic AMP (cAMP)-specific, cyclic nucleotide phosphodiesterase (PDE) family. Cyclic nucleotides are important second messengers that regulate and mediate a number of cellular responses to extracellular signals, such as hormones, light, and neurotransmitters. The cyclic nucleotide phosphodiesterases (PDEs) regulate the cellular concentrations of cyclic nucleotides and thereby play a role in signal transduction. This gene encodes a protein that specifically hydrolyzes cAMP. Altered activity of this protein has been associated with schizophrenia and bipolar affective disorder. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Poids moléculaire: 83 kDa

ID gène: 5142

UniProt: Q07343

Pathways: Cellular Response to Molecule of Bacterial Origin, cAMP Metabolic Process, Myometrial Relaxation and Contraction