UAP1 anticorps

N° du produit ABIN2855661

Cet anticorps anti-UAP1 est un anticorps Lapin Polyclonal détectant UAP1 dans WB, IF, ICC et IHC (p). Adapté pour Humain. Ce Primary Antibody a été cité dans 1 publication.

Aperçu rapide pour UAP1 anticorps (ABIN2855661)

Antigène: UAP1 (UDP-N-Acteylglucosamine Pyrophosphorylase 1 (UAP1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp UAP1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-UAP1 anticorps

Réactivité croisée: Humain

Attributs du produit: Rabbit polyclonal antibody to UAP1 (UDP-N-acteylglucosamine pyrophosphorylase 1)
UAP1 antibody [N1C3]

Purification: Purified by antigen-affinity chromatography.

Immunogène: Recombinant protein encompassing a sequence within the center region of human UAP1. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Commentaires:

Positive Control: H1299

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Références pour anticorps anti-UAP1 (ABIN2855661)

Andres, Blong, Evans, Rumachik, Yamaguchi, Pham, Thompson, Kohler, Bertozzi: "Chemical Modulation of Protein O-GlcNAcylation via OGT Inhibition Promotes Human Neural Cell Differentiation." dans: ACS chemical biology, Vol. 12, Issue 8, pp. 2030-2039, (2018) (PubMed).

Détails sur UAP1

Antigène: UAP1 (UDP-N-Acteylglucosamine Pyrophosphorylase 1 (UAP1))

Autre désignation: UDP-N-acetylglucosamine pyrophosphorylase 1

Sujet: Converts UDP and GlcNAc-1-P into UDP-GlcNAc, and UDP and GalNAc-1-P into UDP-GalNAc. Isoform AGX1 has 2 to 3 times higher activity towards GalNAc-1-P, while isoform AGX2 has 8 times more activity towards GlcNAc-1-P.

Cellular Localization: Cytoplasm

Poids moléculaire: 59 kDa

ID gène: 6675

UniProt: Q16222