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Seladin 1 anticorps

Cet anticorps anti-Seladin 1 est un anticorps Lapin Polyclonal détectant Seladin 1 dans WB, IHC (p), IF et ICC. Adapté pour Humain.
N° du produit ABIN2855685

Aperçu rapide pour Seladin 1 anticorps (ABIN2855685)

Antigène

Voir toutes Seladin 1 (DHCR24) Anticorps
Seladin 1 (DHCR24) (24-Dehydrocholesterol Reductase (DHCR24))

Reactivité

  • 43
  • 36
  • 27
  • 4
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
Humain

Hôte

  • 41
  • 2
Lapin

Clonalité

  • 43
Polyclonal

Conjugué

  • 17
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp Seladin 1 est non-conjugé

Application

  • 31
  • 13
  • 13
  • 5
  • 3
  • 3
  • 3
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Immunocytochemistry (ICC)
  •  Réactivité croisée

    Humain, Souris, Rat

    Attributs du produit

    Rabbit Polyclonal antibody to Seladin 1 (24-dehydrocholesterol reductase)
    Seladin 1 antibody [N1C2]

    Purification

    Purified by antigen-affinity chromatography.

    Immunogène

    Recombinant protein encompassing a sequence within the center region of human Seladin 1. The exact sequence is proprietary.

    Isotype

    IgG
  • Indications d'application

    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1.47 mg/mL

    Buffer

    1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300

    Agent conservateur

    ProClin

    Précaution d'utilisation

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    4 °C,-20 °C

    Stockage commentaire

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Antigène

    Seladin 1 (DHCR24) (24-Dehydrocholesterol Reductase (DHCR24))

    Autre désignation

    24-dehydrocholesterol reductase

    Sujet

    This gene encodes a flavin adenine dinucleotide (FAD)-dependent oxidoreductase which catalyzes the reduction of the delta-24 double bond of sterol intermediates during cholesterol biosynthesis. The protein contains a leader sequence that directs it to the endoplasmic reticulum membrane. Missense mutations in this gene have been associated with desmosterolosis. Also, reduced expression of the gene occurs in the temporal cortex of Alzheimer disease patients and overexpression has been observed in adrenal gland cancer cells.

    Cellular Localization: Endoplasmic reticulum membrane , Golgi apparatus membrane

    Poids moléculaire

    60 kDa

    ID gène

    1718

    UniProt

    Q15392
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