L3MBTL1 anticorps (Center)

N° du produit ABIN2855703

Détail du produit anti-L3MBTL1 anticorps

Antigène: L3MBTL1 (L(3)mbt-Like 1 (L3MBTL1))

Épitope: Center

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp L3MBTL1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

Réactivité croisée: Souris

Réactivité croisée (Details): mouse (88 %)

Attributs du produit: Rabbit polyclonal antibody to L3MBTL (l(3)mbt-like (Drosophila))
L3MBTL antibody

Purification: Purified by antigen-affinity chromatography.

Immunogène: Recombinant protein encompassing a sequence within the center region of human L3MBTL. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: Suggested dilution Reference ICC/IF 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* Western blot1:500-1:3000*

Commentaires:

Positive Control: HeLaS3 , human L3MBTL-transfected 293T

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Références pour anticorps anti-L3MBTL1 (ABIN2855703)

Lu, Periz, Lu, Tang, Liu, Zhang, Shah, Thombre, Aljumaah, Li, Mojsilovic-Petrovic, Ji, Johnson, Kalb, Wang: "L3MBTL1 regulates ALS/FTD-associated proteotoxicity and quality control." dans: Nature neuroscience, Vol. 22, Issue 6, pp. 875-886, (2019) (PubMed).

Détails sur L3MBTL1

Antigène: L3MBTL1 (L(3)mbt-Like 1 (L3MBTL1))

Autre désignation: L3MBTL (L3MBTL1 Produits)

Synonymes: anticorps C630004G01, anticorps L3mbtl, anticorps mKIAA0681, anticorps H-L(3)MBT, anticorps L3MBTL, anticorps ZC2HC3, anticorps dJ138B7.3, anticorps RGD1307316, anticorps l(3)mbt-like (Drosophila), anticorps L3MBTL1, histone methyl-lysine binding protein, anticorps l(3)mbt-like 1 (Drosophila), anticorps L3mbtl1, anticorps L3MBTL1

Sujet: This gene encodes the homolog of a protein identified in Drosophila as a suppressor of malignant transformation of neuroblasts and ganglion-mother cells in the optic centers of the brain. This gene product is localized to condensed chromosomes in mitotic cells. Overexpression of this gene in a glioma cell line results in improper nuclear segregation and cytokinesis producing multinucleated cells. Alternatively spliced transcript variants encoding different isoforms have been identified.

Cellular Localization: Nucleus

Poids moléculaire: 84 kDa

ID gène: 26013

Pathways: Chromatin Binding