NOX1 anticorps

N° du produit ABIN2855720

L’anticorps Lapin Polyclonal anti-NOX1 a été validé pour WB, ICC, IHC (p) et IF. Il convient pour détecter NOX1 dans des échantillons de Humain. Il y a 2+ publications disponibles.

Aperçu rapide pour NOX1 anticorps (ABIN2855720)

Antigène: NOX1 (NADPH Oxidase 1 (NOX1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NOX1 est non-conjugé

Application: Western Blotting (WB), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Détail du produit anti-NOX1 anticorps

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Rabbit Polyclonal antibody to NOX1 (NADPH oxidase 1)
NOX1 antibody

Purification: Purified by antigen-affinity chromatography.

Immunogène: Recombinant protein encompassing a sequence within the center region of human NOX1. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Commentaires:

Positive Control: JC , BCL-1 , 293T , A431 , HeLa

Validation: Orthogonal

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.19 mg/mL

Buffer: 1XPBS pH 7, 20 % Glycerol, 0.025 % ProClin 300

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Références pour anticorps anti-NOX1 (ABIN2855720)

Liang, Ma, Zhong, Dhar, Liu, Xu, Koyama, Nishio, Karin, Karin, Mccubbin, Zhang, Hu, Yang, Chen, Ganguly, Lan, Karin, Kisseleva, Brenner: "NADPH Oxidase 1 in Liver Macrophages Promotes Inflammation and Tumor Development in Mice." dans: Gastroenterology, Vol. 156, Issue 4, pp. 1156-1172.e6, (2019) (PubMed).

Sandrini, Ieraci, Amadio, Popoli, Tremoli, Barbieri: "Apocynin Prevents Abnormal Megakaryopoiesis and Platelet Activation Induced by Chronic Stress." dans: Oxidative medicine and cellular longevity, Vol. 2017, pp. 9258937, (2018) (PubMed).

Détails sur NOX1

Antigène: NOX1 (NADPH Oxidase 1 (NOX1))

Autre désignation: NADPH oxidase 1

Sujet: Voltage-gated proton (hydrogen) channels play an important role in cellular defense against acidic stress. They are unique among ion channels with respect to their extremely high selectivity, marked temperature dependence, and unitary conductance, which is 3 orders of magnitude lower than that of most other ion channels. NOX1 is a homolog of the catalytic subunit of the superoxide-generating NADPH oxidase of phagocytes, gp91phox. Two transcript variants encoding different isoforms have been found for this gene.

Cellular Localization: Membrane, Multi-pass membrane protein

Poids moléculaire: 65 kDa

ID gène: 27035

UniProt: Q9Y5S8

Pathways: Regulation of Systemic Arterial Blood Pressure by Hormones, Proton Transport