GLB1 anticorps

N° du produit ABIN2855812

Cet anticorps Lapin Polyclonal détecte spécifiquement GLB1 dans WB, IF, ICC et IHC (p). Il présente une réactivité envers Humain et a été mentionné dans 1 publication.

Aperçu rapide pour GLB1 anticorps (ABIN2855812)

Antigène: GLB1 (Galactosidase, beta 1 (GLB1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GLB1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-GLB1 anticorps

Réactivité croisée: Humain, Rat

Attributs du produit: Rabbit polyclonal antibody to beta-Gal (galactosidase, beta 1)
beta-Gal antibody [N2C3]

Purification: Purified by antigen-affinity chromatography.

Immunogène: Recombinant protein encompassing a sequence within the center region of human beta-Gal. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Commentaires:

Validation: Orthogonal

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.35 mg/mL

Buffer: 1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.025 % ProClin 300

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Références pour anticorps anti-GLB1 (ABIN2855812)

Chang, Su, Chen, Chen, Chen, Hsiao: "Secretory RAB GTPase 3C modulates IL6-STAT3 pathway to promote colon cancer metastasis and is associated with poor prognosis." dans: Molecular cancer, Vol. 16, Issue 1, pp. 135, (2018) (PubMed).

Détails sur GLB1

Antigène: GLB1 (Galactosidase, beta 1 (GLB1))

Autre désignation: galactosidase beta 1

Sujet: This gene encodes beta-galactosidase-1, a lysosomal enzyme that hydrolyzes the terminal beta-galactose from ganglioside substrates and other glycoconjugates. Defects in this gene are the cause of GM1-gangliosidosis and Morquio B syndrome. Multiple transcript variants encoding different isoforms have been found for this gene.

Cellular Localization: Isoform 1: Lysosome , Isoform 2: Cytoplasm , perinuclear region

Poids moléculaire: 76 kDa

ID gène: 2720

UniProt: P16278

Pathways: Glycosaminoglycan Metabolic Process