POLR2A/RPB1 anticorps (C-Term)
Aperçu rapide pour POLR2A/RPB1 anticorps (C-Term) (ABIN2855904)
Antigène
Voir toutes POLR2A/RPB1 (POLR2A) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- C-Term
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Réactivité croisée
- Souris, Boeuf (Vache)
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Réactivité croisée (Details)
- Mouse (100 %), Bovine (100 %)
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Attributs du produit
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Rabbit polyclonal antibody to POLR2A (polymerase (RNA) II (DNA directed) polypeptide A, 220 kDa)
RPB1 antibody [C3], C-term -
Purification
- Purified by antigen-affinity chromatography.
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Immunogène
- Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human RPB1. The exact sequence is proprietary.
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Isotype
- IgG
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Indications d'application
- Suggested dilution Reference Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceWestern blot1:500-1:3000*
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Commentaires
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Positive Control: 293T , A431 , H1299 , HepG2 , Raji
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.72 mg/mL
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Buffer
- 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
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Agent conservateur
- Thimerosal (Merthiolate)
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Précaution d'utilisation
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- POLR2A/RPB1 (POLR2A) (RNA Polymerase II Subunit RPB1 (POLR2A))
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Autre désignation
- POLR2A
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Sujet
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This gene encodes the largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene contains a carboxy terminal domain composed of heptapeptide repeats that are essential for polymerase activity. These repeats contain serine and threonine residues that are phosphorylated in actively transcribing RNA polymerase. In addition, this subunit, in combination with several other polymerase subunits, forms the DNA binding domain of the polymerase, a groove in which the DNA template is transcribed into RNA.
Cellular Localization: Nucleus -
Poids moléculaire
- 217 kDa
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ID gène
- 5430
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Pathways
- Regulatory RNA Pathways
Antigène
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