BPNT1 anticorps
Aperçu rapide pour BPNT1 anticorps (ABIN2856006)
Antigène
Voir toutes BPNT1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Réactivité croisée
- Humain, Souris
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Attributs du produit
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Rabbit Polyclonal antibody to BPNT1 (3'(2'), 5'-bisphosphate nucleotidase 1)
BPNT1 antibody [N1C3] -
Purification
- Purified by antigen-affinity chromatography.
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Immunogène
- Recombinant protein encompassing a sequence within the center region of human BPNT1. The exact sequence is proprietary.
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Isotype
- IgG
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Indications d'application
- WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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Commentaires
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Positive Control: Mouse liver , HeLaS3
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.7 mg/mL
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Buffer
- 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
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Agent conservateur
- Thimerosal (Merthiolate)
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Précaution d'utilisation
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- BPNT1 (3'(2'), 5'-Bisphosphate Nucleotidase 1 (BPNT1))
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Autre désignation
- 3'(2'), 5'-bisphosphate nucleotidase 1
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Sujet
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BPNT1, also called bisphosphate 3-prime-nucleotidase, or BPntase, is a member of a magnesium-dependent phosphomonoesterase family. Lithium, a major drug used to treat manic depression, acts as an uncompetitive inhibitor of BPntase. The predicted human protein is 92 % identical to mouse BPntase. BPntase's physiologic role in nucleotide metabolism may be regulated by inositol signaling pathways. The inhibition of human BPntase may account for lithium-induced nephrotoxicity.
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Poids moléculaire
- 33 kDa
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ID gène
- 10380
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UniProt
- O95861
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Pathways
- Inositol Metabolic Process
Antigène
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