MTHFD2 anticorps
Aperçu rapide pour MTHFD2 anticorps (ABIN2856008)
Antigène
Voir toutes MTHFD2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Classe de qualité
-
-
Réactivité croisée
- Humain
-
Attributs du produit
-
Rabbit Polyclonal antibody to MTHFD2 (methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase)
MTHFD2 antibody [N1C3] -
Purification
- Purified by antigen-affinity chromatography.
-
Immunogène
- Recombinant protein encompassing a sequence within the center region of human MTHFD2. The exact sequence is proprietary.
-
Isotype
- IgG
-
-
-
-
Indications d'application
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
-
Commentaires
-
Positive Control: 293T
Validation: KO/KD
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Concentration
- 0.13 mg/mL
-
Buffer
- 1XPBS, 1 % BSA, 20 % Glycerol ( pH 7)., 0.025 % ProClin 300
-
Agent conservateur
- ProClin
-
Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Stock
- 4 °C,-20 °C
-
Stockage commentaire
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
-
-
- MTHFD2 (Methylenetetrahydrofolate Dehydrogenase (NADP+ Dependent) 2, Methenyltetrahydrofolate Cyclohydrolase (MTHFD2))
-
Autre désignation
- methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
-
Sujet
-
This gene encodes a nuclear-encoded mitochondrial bifunctional enzyme with methylenetetrahydrofolate dehydrogenase and methenyltetrahydrofolate cyclohydrolase activities. The enzyme functions as a homodimer and is unique in its absolute requirement for magnesium and inorganic phosphate. Formation of the enzyme-magnesium complex allows binding of NAD. Alternative splicing results in two different transcripts, one protein-coding and the other not protein-coding. This gene has a pseudogene on chromosome 7.
Cellular Localization: Mitochondrion -
Poids moléculaire
- 38 kDa
-
ID gène
- 10797
-
UniProt
- P13995
Antigène
-