NANS anticorps (Center)
Aperçu rapide pour NANS anticorps (Center) (ABIN2856066)
Antigène
Voir toutes NANS AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Center
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Réactivité croisée
- Souris, Poulet, Porc, Rat (Rattus), Boeuf (Vache)
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Réactivité croisée (Details)
- Mouse (97 %), Chicken (88 %), Pig (97 %), Rat (97 %), Bovine (97 %)
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Attributs du produit
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Rabbit polyclonal antibody to NANS (N-acetylneuraminic acid synthase)
NANS antibody [N1C3] -
Purification
- Purified by antigen-affinity chromatography.
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Immunogène
- Recombinant protein encompassing a sequence within the center region of human NANS. The exact sequence is proprietary.
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Isotype
- IgG
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Indications d'application
- Suggested dilution Reference ICC/IF 1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*
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Commentaires
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Positive Control: A431 , HeLa , HepG2
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.21 mg/mL
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Buffer
- 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
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Agent conservateur
- Thimerosal (Merthiolate)
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Précaution d'utilisation
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- NANS (N-Acetylneuraminic Acid Synthase (NANS))
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Autre désignation
- NANS
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Sujet
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This gene encodes an enzyme that functions in the biosynthetic pathways of sialic acids. In vitro, the encoded protein uses N-acetylmannosamine 6-phosphate and mannose 6-phosphate as substrates to generate phosphorylated forms of N-acetylneuraminic acid (Neu5Ac) and 2-keto-3-deoxy-D-glycero-D-galacto-nononic acid (KDN), respectively, however, it exhibits much higher activity toward the Neu5Ac phosphate product. In insect cells, expression of this gene results in Neu5Ac and KDN production. This gene is related to the E. coli sialic acid synthase gene neuB, and it can partially restore sialic acid synthase activity in an E. coli neuB-negative mutant.
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Poids moléculaire
- 40 kDa
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ID gène
- 54187
Antigène
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