PROC anticorps
Aperçu rapide pour PROC anticorps (ABIN2856203)
Antigène
Voir toutes PROC AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Réactivité croisée
- Humain
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Attributs du produit
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Rabbit Polyclonal antibody to Protein C (vitamin K-dependent protein C)
Protein C antibody -
Purification
- Purified by antigen-affinity chromatography.
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Immunogène
- Recombinant protein encompassing a sequence within the center region of human Protein C. The exact sequence is proprietary.
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Isotype
- IgG
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Indications d'application
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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Commentaires
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Validation: Orthogonal
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- 1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.01 % Thimerosal
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Agent conservateur
- Thimerosal (Merthiolate)
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Précaution d'utilisation
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- PROC (Vitamin K-dependent protein C (PROC))
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Autre désignation
- protein C, inactivator of coagulation factors Va and VIIIa
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Sujet
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The PROC gene encodes protein C (EC 3.4.21.69), a vitamin K-dependent plasma glycoprotein that is a key component of the anticoagulant system. Protein C is cleaved to its activated form, 'activated protein C' (APC) on endothelial cells by the thrombin-thrombomodulin complex (MIM 176930, MIM 188040) and then acts as a serine protease to degrade the activated forms of coagulation factors V (F5, MIM 612309) and VIII (F8, see MIM 306700). Protein S (PROS1, MIM 176880), also a vitamin K-dependent plasma protein, functions as a cofactor to activated protein C.[supplied by OMIM]
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Poids moléculaire
- 52 kDa
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ID gène
- 5624
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UniProt
- P04070
Antigène
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