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Adenylate Kinase 1 anticorps

Cet anticorps anti-Adenylate Kinase 1 est un anticorps Lapin Polyclonal détectant Adenylate Kinase 1 dans WB et IHC (p). Adapté pour Humain.
N° du produit ABIN2856252

Aperçu rapide pour Adenylate Kinase 1 anticorps (ABIN2856252)

Antigène

Voir toutes Adenylate Kinase 1 (AK1) Anticorps
Adenylate Kinase 1 (AK1)

Reactivité

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Humain

Hôte

  • 81
  • 11
  • 6
Lapin

Clonalité

  • 88
  • 10
Polyclonal

Conjugué

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Cet anticorp Adenylate Kinase 1 est non-conjugé

Application

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Classe de qualité

KO Validated
  •  Réactivité croisée

    Humain, Souris

    Attributs du produit

    Rabbit Polyclonal antibody to Adenylate kinase 1 (adenylate kinase 1)
    Adenylate kinase 1 antibody [N1C3]

    Purification

    Purified by antigen-affinity chromatography.

    Immunogène

    Recombinant protein encompassing a sequence within the center region of human Adenylate kinase 1. The exact sequence is proprietary.

    Isotype

    IgG
  • Indications d'application

    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    Commentaires

    Positive Control: Mouse brown adipose tissue

    Validation: KO/KD

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    0.4 mg/mL

    Buffer

    0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

    Agent conservateur

    Thimerosal (Merthiolate)

    Précaution d'utilisation

    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    4 °C,-20 °C

    Stockage commentaire

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Antigène

    Adenylate Kinase 1 (AK1)

    Autre désignation

    adenylate kinase 1

    Sujet

    Adenylate kinase is an enzyme involved in regulating the adenine nucleotide composition within a cell by catalyzing the reversible transfer of phosphate group among adinine nucleotides. Three isozymes of adenylate kinase have been identified in vertebrates, adenylate isozyme 1 (AK1), 2 (AK2) and 3 (AK3). AK1 is found in the cytosol of skeletal muscle, brain and erythrocytes, whereas AK2 and AK3 are found in the mitochondria of other tissues including liver and heart. AK1 was identified because of its association with a rare genetic disorder causing nonspherocytic hemolytic anemia where a mutation in the AK1 gene was found to reduce the catalytic activity of the enzyme.

    Cellular Localization: Cytoplasm

    Poids moléculaire

    22 kDa

    ID gène

    203

    UniProt

    P00568

    Pathways

    Nucleotide Phosphorylation, Ribonucleoside Biosynthetic Process
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