GSTZ1 anticorps

N° du produit ABIN2856258

Cet anticorps anti-GSTZ1 est un anticorps Lapin Polyclonal détectant GSTZ1 dans WB, IF, IHC (p) et ICC. Adapté pour Humain. Ce Primary Antibody a été cité dans 2+ publications.

Aperçu rapide pour GSTZ1 anticorps (ABIN2856258)

Antigène: GSTZ1 (Glutathione Transferase zeta 1 (Maleylacetoacetate Isomerase) (GSTZ1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GSTZ1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Classe de qualité: KO Validated

Détail du produit anti-GSTZ1 anticorps

Réactivité croisée: Humain

Attributs du produit: Rabbit Polyclonal antibody to GSTZ1 (glutathione transferase zeta 1)
GSTZ1 antibody [N1C3]

Purification: Purified by antigen-affinity chromatography.

Immunogène: Recombinant protein encompassing a sequence within the center region of human GSTZ1. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Commentaires:

Positive Control: 293T

Validation: KO/KD, Orthogonal, Overexpression

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.98 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Références pour anticorps anti-GSTZ1 (ABIN2856258)

Lei, Wang, Tang, Wang: "GSTZ1-1 downregulates Wnt/β-catenin signalling in hepatocellular carcinoma cells." dans: FEBS open bio, Vol. 10, Issue 1, pp. 6-17, (2020) (PubMed).

Li, Wang, Yang, Lei, Yang, Liang, Chen, Xia, Wang, Tang: "GSTZ1 deficiency promotes hepatocellular carcinoma proliferation via activation of the KEAP1/NRF2 pathway." dans: Journal of experimental & clinical cancer research : CR, Vol. 38, Issue 1, pp. 438, (2020) (PubMed).

Détails sur GSTZ1

Antigène: GSTZ1 (Glutathione Transferase zeta 1 (Maleylacetoacetate Isomerase) (GSTZ1))

Autre désignation: glutathione S-transferase zeta 1

Sujet: This gene is a member of the glutathione S-transferase (GSTs) super-family which encodes multifunctional enzymes important in the detoxification of electrophilic molecules, including carcinogens, mutagens, and several therapeutic drugs, by conjugation with glutathione. This enzyme also plays a significant role in the catabolism of phenylalanine and tyrosine. Thus defects in this enzyme may lead to severe metabolic disorders including alkaptonuria, phenylketonuria and tyrosinaemia. Several transcript variants of this gene encode multiple protein isoforms.

Cellular Localization: Cytoplasm

Poids moléculaire: 24 kDa

ID gène: 2954

UniProt: O43708