IRF8 anticorps (C-Term)
Aperçu rapide pour IRF8 anticorps (C-Term) (ABIN2856323)
Antigène
Voir toutes IRF8 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- C-Term
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Réactivité croisée
- Humain
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Attributs du produit
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Rabbit polyclonal antibody to IRF8 (interferon regulatory factor 8)
IRF8 antibody [C3], C-term -
Purification
- Purified by antigen-affinity chromatography.
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Immunogène
- Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human IRF8. The exact sequence is proprietary.
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Isotype
- IgG
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Indications d'application
- WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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Commentaires
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Positive Control: THP-1 nuclear extract
Validation: Comparison, Orthogonal
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- 1XPBS ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
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Agent conservateur
- Thimerosal (Merthiolate)
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Précaution d'utilisation
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- IRF8 (Interferon Regulatory Factor 8 (IRF8))
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Autre désignation
- interferon regulatory factor 8
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Sujet
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Interferon consensus sequence-binding protein (ICSBP) is a transcription factor of the interferon (IFN) regulatory factor (IRF) family. Proteins of this family are composed of a conserved DNA-binding domain in the N-terminal region and a divergent C-terminal region that serves as the regulatory domain. The IRF family proteins bind to the IFN-stimulated response element (ISRE) and regulate expression of genes stimulated by type I IFNs, namely IFN-alpha and IFN-beta. IRF family proteins also control expression of IFN-alpha and IFN-beta-regulated genes that are induced by viral infection.
Cellular Localization: Nucleus -
Poids moléculaire
- 48 kDa
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ID gène
- 3394
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UniProt
- Q02556
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Pathways
- Cellular Response to Molecule of Bacterial Origin
Antigène
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