CHMP5 anticorps

N° du produit ABIN2856420

Cet anticorps anti-CHMP5 est un anticorps Lapin Polyclonal détectant CHMP5 dans WB, IF, IHC (p), ICC et IP. Adapté pour Humain.

Aperçu rapide pour CHMP5 anticorps (ABIN2856420)

Antigène: CHMP5 (Charged Multivesicular Body Protein 5 (CHMP5))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CHMP5 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunoprecipitation (IP)

Détail du produit anti-CHMP5 anticorps

Réactivité croisée: Humain, Souris

Attributs du produit: Rabbit Polyclonal antibody to CHMP5 (chromatin modifying protein 5)
CHMP5 antibody [N1C3]

Purification: Purified by antigen-affinity chromatography.

Immunogène: Recombinant protein encompassing a sequence within the center region of human CHMP5. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Commentaires:

Positive Control: 293T , A431 , H1299 , HeLaS3 , HepG2

Validation: Comparison, Orthogonal

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.7 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Détails sur CHMP5

Antigène: CHMP5 (Charged Multivesicular Body Protein 5 (CHMP5))

Autre désignation: charged multivesicular body protein 5

Sujet: CHMP5 belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A (MIM 164010), is required for both MVB formation and regulation of cell cycle progression (Tsang et al., 2006 [PubMed 16730941]).[supplied by OMIM]

Cellular Localization: Cytoplasm , cytosol , Endosome membrane, Peripheral membrane protein , Cytoplasm , cytosol , Endosome membrane

Poids moléculaire: 25 kDa

ID gène: 51510

UniProt: Q9NZZ3