SPOP-B anticorps (Center)
Aperçu rapide pour SPOP-B anticorps (Center) (ABIN2856462)
Antigène
Voir toutes SPOP-B AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Center
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Réactivité croisée
- Rat (Rattus), Xenopus tropicalis, Macaque rhésus, Boeuf (Vache)
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Réactivité croisée (Details)
- Rat (100 %), Xenopus Tropicalis (100 %), Rhesus Monkey (100 %), Bovine (100 %)
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Attributs du produit
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Rabbit Polyclonal antibody to SPOP (speckle-type POZ protein)
SPOP antibody [N1C1] -
Purification
- Purified by antigen-affinity chromatography.
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Immunogène
- Recombinant protein encompassing a sequence within the center region of human SPOP. The exact sequence is proprietary.
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Isotype
- IgG
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Indications d'application
- Suggested dilution Reference Immunohistochemistry Assay-dependent dilution Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceImmunohistochemistryAssay-dependent dilution Western blot1:500-1:3000*
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Commentaires
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Positive Control: 293T , Raji , mouse brain
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
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Agent conservateur
- Thimerosal (Merthiolate)
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Précaution d'utilisation
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- SPOP-B (Speckle-Type POZ Protein (SPOP-B))
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Autre désignation
- SPOP
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Sujet
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This gene encodes a protein that may modulate the transcriptional repression activities of death-associated protein 6 (DAXX), which interacts with histone deacetylase, core histones, and other histone-associated proteins. In mouse, the encoded protein binds to the putative leucine zipper domain of macroH2A1.2, a variant H2A histone that is enriched on inactivated X chromosomes. The BTB/POZ domain of this protein has been shown in other proteins to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes. Alternative splicing of this gene results in multiple transcript variants encoding the same protein.
Cellular Localization: Nucleus -
Poids moléculaire
- 42 kDa
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ID gène
- 8405
Antigène
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