ZWINT anticorps (Center)
Aperçu rapide pour ZWINT anticorps (Center) (ABIN2856493)
Antigène
Voir toutes ZWINT AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Center
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Attributs du produit
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Rabbit Polyclonal antibody to ZWINT (ZW10 interactor)
ZWINT antibody -
Purification
- Purified by antigen-affinity chromatography.
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Immunogène
- Recombinant protein encompassing a sequence within the center region of human ZWINT. The exact sequence is proprietary.
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Isotype
- IgG
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Indications d'application
- Suggested dilution Reference ICC/IF 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* Western blot1:500-1:3000*
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Commentaires
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Positive Control: 293T , Molt-4 , Raji
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
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Agent conservateur
- Thimerosal (Merthiolate)
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Précaution d'utilisation
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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: "Cep57 is a Mis12-interacting kinetochore protein involved in kinetochore targeting of Mad1-Mad2." dans: Nature communications, Vol. 7, pp. 10151, (2016) (PubMed).
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: "Cep57 is a Mis12-interacting kinetochore protein involved in kinetochore targeting of Mad1-Mad2." dans: Nature communications, Vol. 7, pp. 10151, (2016) (PubMed).
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- ZWINT (ZW10 Interactor (ZWINT))
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Autre désignation
- ZWINT
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Sujet
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This gene encodes a protein that is clearly involved in kinetochore function although an exact role is not known. It interacts with ZW10, another kinetochore protein, possibly regulating the association between ZW10 and kinetochores. The encoded protein localizes to prophase kinetochores before ZW10 does and it remains detectable on the kinetochore until late anaphase. It has a uniform distribution in the cytoplasm of interphase cells. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Cellular Localization: Nucleus , Kinetochore -
Poids moléculaire
- 31 kDa
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ID gène
- 11130
Antigène
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