UNC13D anticorps (C-Term)

N° du produit ABIN2856569

L’anticorps Lapin Polyclonal anti-UNC13D a été validé pour WB, IF, IHC (p) et ICC. Il convient pour détecter UNC13D dans des échantillons de Humain.

Aperçu rapide pour UNC13D anticorps (C-Term) (ABIN2856569)

Antigène: UNC13D (Unc-13 Homolog D (UNC13D))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp UNC13D est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Détail du produit anti-UNC13D anticorps

Épitope: C-Term

Réactivité croisée: Humain

Attributs du produit: Rabbit Polyclonal antibody to Munc 13-4 (unc-13 homolog D (C. elegans))
Munc 13-4 antibody [C3], C-term

Purification: Purified by antigen-affinity chromatography.

Immunogène: Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human Munc 13-4. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Commentaires:

Positive Control: Jurkat , K562

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Détails sur UNC13D

Antigène: UNC13D (Unc-13 Homolog D (UNC13D))

Autre désignation: unc-13 homolog D

Sujet: This gene encodes a protein that is a member of the UNC13 family, containing similar domain structure as other family members but lacking an N-terminal phorbol ester-binding C1 domain present in other Munc13 proteins. The protein appears to play a role in vesicle maturation during exocytosis and is involved in regulation of cytolytic granules secretion. Mutations in this gene are associated with familial hemophagocytic lymphohistiocytosis type 3, a genetically heterogeneous, rare autosomal recessive disorder.

Cellular Localization: Cytoplasm , Membrane, Peripheral membrane protein

Poids moléculaire: 123 kDa

ID gène: 201294

UniProt: Q70J99

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process