HRH2 anticorps (N-Term)

N° du produit ABIN2856570

Cet anticorps anti-HRH2 est un anticorps Lapin Polyclonal détectant HRH2 dans WB, IF, IHC (p), IHC, ICC et FACS. Adapté pour Humain. Ce Primary Antibody a été cité dans 2+ publications.

Aperçu rapide pour HRH2 anticorps (N-Term) (ABIN2856570)

Antigène: HRH2 (Histamine Receptor H2 (HRH2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HRH2 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FACS)

Détail du produit anti-HRH2 anticorps

Épitope: N-Term

Réactivité croisée: Humain, Rat

Attributs du produit: Rabbit Polyclonal antibody to Histamine H2 Receptor (histamine receptor H2)
Histamine H2 Receptor antibody [N1], N-term

Purification: Purified by antigen-affinity chromatography.

Immunogène: Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human Histamine H2 Receptor. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Commentaires:

Positive Control: NT2D1 , PC-3 , U87-MG , SK-N-SH

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.75 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Références pour anticorps anti-HRH2 (ABIN2856570)

Adderley, Zhang, Breslin: "Involvement of the H1 Histamine Receptor, p38 MAP Kinase, Myosin Light Chains Kinase, and Rho/ROCK in Histamine-Induced Endothelial Barrier Dysfunction." dans: Microcirculation (New York, N.Y. : 1994), Vol. 22, Issue 4, pp. 237-48, (2016) (PubMed).

Kurtz, Moor, Souza-Smith, Breslin: "Involvement of H1 and H2 receptors and soluble guanylate cyclase in histamine-induced relaxation of rat mesenteric collecting lymphatics." dans: Microcirculation (New York, N.Y. : 1994), Vol. 21, Issue 7, pp. 593-605, (2015) (PubMed).

Détails sur HRH2

Antigène: HRH2 (Histamine Receptor H2 (HRH2))

Autre désignation: histamine receptor H2

Sujet: Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by histamine receptors H1, H2, H3 and H4. Histamine receptor H2 belongs to the family 1 of G protein-coupled receptors. It is an integral membrane protein and stimulates gastric acid secretion. It also regulates gastrointestinal motility and intestinal secretion and is thought to be involved in regulating cell growth and differentiation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Cellular Localization: Cell membrane, Multi-pass membrane protein

Poids moléculaire: 40 kDa

ID gène: 3274

UniProt: P25021