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INHBA anticorps (C-Term)

KO Validated INHBA Reactivité: Humain WB, ICC, IF, IHC (p) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2856600
  • Antigène Voir toutes INHBA Anticorps
    INHBA (Inhibin, beta A (INHBA))
    Épitope
    • 10
    • 8
    • 7
    • 7
    • 7
    • 6
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivité
    • 59
    • 30
    • 25
    • 10
    • 8
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 79
    • 11
    Lapin
    Clonalité
    • 79
    • 12
    Polyclonal
    Conjugué
    • 49
    • 16
    • 11
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp INHBA est non-conjugé
    Application
    • 79
    • 44
    • 34
    • 21
    • 20
    • 14
    • 7
    • 6
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
     Réactivité croisée
    Humain
    Attributs du produit
    Rabbit Polyclonal antibody to Inhibin beta A (inhibin, beta A)
    Inhibin beta A antibody
    Purification
    Purified by antigen-affinity chromatography.
    Classe de qualité
    KO Validated
    Immunogène
    Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human Inhibin beta A. The exact sequence is proprietary.
    Isotype
    IgG
    Top Product
    Discover our top product INHBA Anticorps primaire
  • Indications d'application
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Commentaires

    Validation: KO/KD

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.66 mg/mL
    Buffer
    1XPBS pH 7, 20 % Glycerol, 0.025 % ProClin 300
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Antigène
    INHBA (Inhibin, beta A (INHBA))
    Autre désignation
    inhibin subunit beta A (INHBA Produits)
    Synonymes
    anticorps EDF, anticorps FRP, anticorps actba, anticorps inhba, anticorps inhbaa-001, anticorps edf, anticorps frp, anticorps INHB, anticorps inhbal, anticorps zgc:158348, anticorps inhibin beta A subunit, anticorps inhibin beta-A, anticorps inhibin, beta Aa, anticorps inhibin beta A, anticorps inhibin, beta Ab, anticorps INHBA, anticorps Inhba, anticorps inhbaa, anticorps inhba, anticorps inhbab
    Sujet
    The inhibin beta A subunit joins the alpha subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumor-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. Because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone. Furthermore, the beta A subunit forms a homodimer, activin A, and also joins with a beta B subunit to form a heterodimer, activin AB, both of which stimulate FSH secretion. Finally, it has been shown that the beta A subunit mRNA is identical to the erythroid differentiation factor subunit mRNA and that only one gene for this mRNA exists in the human genome.

    Cellular Localization: Secreted
    Poids moléculaire
    47 kDa
    ID gène
    3624
    UniProt
    P08476
    Pathways
    Hormone Transport, Peptide Hormone Metabolism, Hormone Activity, Negative Regulation of Hormone Secretion, Autophagy
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