Liver Arginase anticorps

N° du produit ABIN2856661

Cet anticorps Lapin Polyclonal détecte spécifiquement Liver Arginase dans WB, ELISA, IF, IP, FACS, IHC (p), ICC et IHC (fro). Il présente une réactivité avec des échantillons de Humain. Il a été cité dans 11+ publications.

Aperçu rapide pour Liver Arginase anticorps (ABIN2856661)

Antigène: Liver Arginase (ARG1) (Arginase, Liver (ARG1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Liver Arginase est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))

Classe de qualité: KO Validated

Détail du produit anti-Liver Arginase anticorps

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Rabbit Polyclonal antibody to Arginase 1 (arginase, liver)
Arginase 1 antibody

Purification: Purified by antigen-affinity chromatography.

Immunogène: Full length human Arginase 1 Recombinant protein.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IHC-Fr: 1:100-1:1000. FACS: 1:50-1:200. IP: 1:100-1:1000. ELISA: 1:1000-1:10000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Commentaires:

Positive Control: HepG2

Validation: KO/KD, Orthogonal

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.26 mg/mL

Buffer: 1XPBS pH 7, 1 % BSA, 20 % Glycerol, 0.025 % ProClin 300

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Références pour anticorps anti-Liver Arginase (ABIN2856661)

Scherwitzl, Opp, Hurtado, Pampeno, Loomis, Kannan, Yu, Meruelo: "Sindbis Virus with Anti-OX40 Overcomes the Immunosuppressive Tumor Microenvironment of Low-Immunogenic Tumors." dans: Molecular therapy oncolytics, Vol. 17, pp. 431-447, (2020) (PubMed).

Glass, Masjedi, Dudzinski, Wilson, Duvall, Yull, Giorgio: "Optimizing Mannose "Click" Conjugation to Polymeric Nanoparticles for Targeted siRNA Delivery to Human and Murine Macrophages." dans: ACS omega, Vol. 4, Issue 16, pp. 16756-16767, (2019) (PubMed).

Gomez, Baylis, Durgin, Newman, Alencar, Mahan, St Hilaire, Müller, Waisman, Francis, Pinteaux, Randolph, Gram, Owens: "Interleukin-1β has atheroprotective effects in advanced atherosclerotic lesions of mice." dans: Nature medicine, Vol. 24, Issue 9, pp. 1418-1429, (2019) (PubMed).

Zhang, Tang, Huang, Zhou, Cui, Weng, Liu, Kim, Lee, Perez-Neut, Ding, Czyz, Hu, Ye, He, Zheng, Shuman, Dai, Ren, Roeder, Becker, Zhao: "Metabolic regulation of gene expression by histone lactylation." dans: Nature, Vol. 574, Issue 7779, pp. 575-580, (2019) (PubMed).

Shen, Li, Ma, Tian, Hong, Zhai, Li, Huang, Shi: "IRAK-M alters the polarity of macrophages to facilitate the survival of Mycobacterium tuberculosis." dans: BMC microbiology, Vol. 17, Issue 1, pp. 185, (2018) (PubMed).

Zhu, Zhang, Lu, Gao, Cai, Sui, Su, Shen, Xie: "Identification of different macrophage subpopulations with distinct activities in a mouse model of oxygen-induced retinopathy." dans: International journal of molecular medicine, Vol. 40, Issue 2, pp. 281-292, (2018) (PubMed).

Wu, Sun, Li, Shen, Zhai, Yu, Chen et al.: "Roles of programmed death protein 1/programmed death-ligand 1 in secondary brain injury after intracerebral hemorrhage in rats: selective modulation of microglia polarization to anti-inflammatory ..." dans: Journal of neuroinflammation, Vol. 14, Issue 1, pp. 36, (2018) (PubMed).

Romano, Parrinello, Vetro, Tibullo, Giallongo, La Cava, Chiarenza, Motta, Caruso, Villari, Tripodo, Cosentino, Ippolito, Consoli, Gallamini, Pileri, Di Raimondo: "The prognostic value of the myeloid-mediated immunosuppression marker Arginase-1 in classic Hodgkin lymphoma." dans: Oncotarget, Vol. 7, Issue 41, pp. 67333-67346, (2018) (PubMed).

Carmona-Fontaine, Deforet, Akkari, Thompson, Joyce, Xavier: "Metabolic origins of spatial organization in the tumor microenvironment." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 114, Issue 11, pp. 2934-2939, (2017) (PubMed).

Beachley, Wolf, Sadtler, Manda, Jacobs, Blatchley, Bader, Pandey, Pardoll, Elisseeff: "Tissue matrix arrays for high-throughput screening and systems analysis of cell function." dans: Nature methods, Vol. 12, Issue 12, pp. 1197-204, (2016) (PubMed).

Harmon, Fronhofer, Keller, Feustel, Zhu, Xu, Avram, Jones, Nagarajan, Lennartz: "Anti-Inflammatory Immune Skewing Is Atheroprotective: Apoe-/-Fc?RIIb-/- Mice Develop Fibrous Carotid Plaques." dans: Journal of the American Heart Association, Vol. 3, Issue 6, (2014) (PubMed).

Détails sur Liver Arginase

Antigène: Liver Arginase (ARG1) (Arginase, Liver (ARG1))

Autre désignation: arginase 1

Sujet: Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exist (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. The type I isoform encoded by this gene, is a cytosolic enzyme and expressed predominantly in the liver as a component of the urea cycle. Inherited deficiency of this enzyme results in argininemia, an autosomal recessive disorder characterized by hyperammonemia.

Cellular Localization: Cytoplasm

Poids moléculaire: 35 kDa

ID gène: 383

UniProt: P05089

Pathways: Cellular Response to Molecule of Bacterial Origin