Liver Arginase anticorps

N° du produit ABIN2856661

Cet anticorps Lapin Polyclonal détecte spécifiquement Liver Arginase dans WB, ELISA, FACS, IF, IHC (p), IP, ICC et IHC (fro). Il présente une réactivité envers Humain et a été mentionné dans 11+ publications.

Aperçu rapide pour Liver Arginase anticorps (ABIN2856661)

Antigène: Liver Arginase (ARG1) (Arginase, Liver (ARG1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Liver Arginase est non-conjugé

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))

Classe de qualité: KO Validated

Détail du produit anti-Liver Arginase anticorps

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Rabbit Polyclonal antibody to Arginase 1 (arginase, liver)
Arginase 1 antibody

Purification: Purified by antigen-affinity chromatography.

Immunogène: Full length human Arginase 1 Recombinant protein.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IHC-Fr: 1:100-1:1000. FACS: 1:50-1:200. IP: 1:100-1:1000. ELISA: 1:1000-1:10000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Commentaires:

Positive Control: HepG2

Validation: KO/KD, Orthogonal

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.26 mg/mL

Buffer: 1XPBS pH 7, 1 % BSA, 20 % Glycerol, 0.025 % ProClin 300

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Références pour anticorps anti-Liver Arginase (ABIN2856661)

Scherwitzl, Opp, Hurtado, Pampeno, Loomis, Kannan, Yu, Meruelo: "Sindbis Virus with Anti-OX40 Overcomes the Immunosuppressive Tumor Microenvironment of Low-Immunogenic Tumors." dans: Molecular therapy oncolytics, Vol. 17, pp. 431-447, (2020) (PubMed).

Glass, Masjedi, Dudzinski, Wilson, Duvall, Yull, Giorgio: "Optimizing Mannose "Click" Conjugation to Polymeric Nanoparticles for Targeted siRNA Delivery to Human and Murine Macrophages." dans: ACS omega, Vol. 4, Issue 16, pp. 16756-16767, (2019) (PubMed).

Gomez, Baylis, Durgin, Newman, Alencar, Mahan, St Hilaire, Müller, Waisman, Francis, Pinteaux, Randolph, Gram, Owens: "Interleukin-1β has atheroprotective effects in advanced atherosclerotic lesions of mice." dans: Nature medicine, Vol. 24, Issue 9, pp. 1418-1429, (2019) (PubMed).

Zhang, Tang, Huang, Zhou, Cui, Weng, Liu, Kim, Lee, Perez-Neut, Ding, Czyz, Hu, Ye, He, Zheng, Shuman, Dai, Ren, Roeder, Becker, Zhao: "Metabolic regulation of gene expression by histone lactylation." dans: Nature, Vol. 574, Issue 7779, pp. 575-580, (2019) (PubMed).

Shen, Li, Ma, Tian, Hong, Zhai, Li, Huang, Shi: "IRAK-M alters the polarity of macrophages to facilitate the survival of Mycobacterium tuberculosis." dans: BMC microbiology, Vol. 17, Issue 1, pp. 185, (2018) (PubMed).

Zhu, Zhang, Lu, Gao, Cai, Sui, Su, Shen, Xie: "Identification of different macrophage subpopulations with distinct activities in a mouse model of oxygen-induced retinopathy." dans: International journal of molecular medicine, Vol. 40, Issue 2, pp. 281-292, (2018) (PubMed).

Wu, Sun, Li, Shen, Zhai, Yu, Chen et al.: "Roles of programmed death protein 1/programmed death-ligand 1 in secondary brain injury after intracerebral hemorrhage in rats: selective modulation of microglia polarization to anti-inflammatory ..." dans: Journal of neuroinflammation, Vol. 14, Issue 1, pp. 36, (2018) (PubMed).

Romano, Parrinello, Vetro, Tibullo, Giallongo, La Cava, Chiarenza, Motta, Caruso, Villari, Tripodo, Cosentino, Ippolito, Consoli, Gallamini, Pileri, Di Raimondo: "The prognostic value of the myeloid-mediated immunosuppression marker Arginase-1 in classic Hodgkin lymphoma." dans: Oncotarget, Vol. 7, Issue 41, pp. 67333-67346, (2018) (PubMed).

Carmona-Fontaine, Deforet, Akkari, Thompson, Joyce, Xavier: "Metabolic origins of spatial organization in the tumor microenvironment." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 114, Issue 11, pp. 2934-2939, (2017) (PubMed).

Beachley, Wolf, Sadtler, Manda, Jacobs, Blatchley, Bader, Pandey, Pardoll, Elisseeff: "Tissue matrix arrays for high-throughput screening and systems analysis of cell function." dans: Nature methods, Vol. 12, Issue 12, pp. 1197-204, (2016) (PubMed).

Harmon, Fronhofer, Keller, Feustel, Zhu, Xu, Avram, Jones, Nagarajan, Lennartz: "Anti-Inflammatory Immune Skewing Is Atheroprotective: Apoe-/-Fc?RIIb-/- Mice Develop Fibrous Carotid Plaques." dans: Journal of the American Heart Association, Vol. 3, Issue 6, (2014) (PubMed).

Détails sur Liver Arginase

Antigène: Liver Arginase (ARG1) (Arginase, Liver (ARG1))

Autre désignation: arginase 1

Sujet: Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exist (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. The type I isoform encoded by this gene, is a cytosolic enzyme and expressed predominantly in the liver as a component of the urea cycle. Inherited deficiency of this enzyme results in argininemia, an autosomal recessive disorder characterized by hyperammonemia.

Cellular Localization: Cytoplasm

Poids moléculaire: 35 kDa

ID gène: 383

UniProt: P05089

Pathways: Cellular Response to Molecule of Bacterial Origin