DNASE1 anticorps

N° du produit ABIN2856669

Cet anticorps anti-DNASE1 Polyclonal Lapin (ABIN2856669) détecte spécifiquement DNASE1 dans WB, IF, ICC et IHC (p). L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour DNASE1 anticorps (ABIN2856669)

Antigène: DNASE1 (Deoxyribonuclease I (DNASE1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DNASE1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-DNASE1 anticorps

Réactivité croisée: Humain, Singe

Attributs du produit: Rabbit Polyclonal antibody to DNase I (deoxyribonuclease I)
DNase I antibody [N1C3]

Purification: Purified by antigen-affinity chromatography.

Immunogène: Recombinant protein corresponding to human DNase I.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.19 mg/mL

Buffer: 1XPBS pH 7, 20 % Glycerol, 0.025 % ProClin 300

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Détails sur DNASE1

Antigène: DNASE1 (Deoxyribonuclease I (DNASE1))

Autre désignation: deoxyribonuclease 1

Sujet: This gene encodes a member of the DNase family. This protein is stored in the zymogen granules of the nuclear envelope and functions by cleaving DNA in an endonucleolytic manner. At least six autosomal codominant alleles have been characterized, DNASE1*1 through DNASE1*6, and the sequence of DNASE1*2 represented in this record. Mutations in this gene have been associated with systemic lupus erythematosus (SLE), an autoimmune disease. A recombinant form of this protein is used to treat the one of the symptoms of cystic fibrosis by hydrolyzing the extracellular DNA in sputum and reducing its viscosity. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.

Cellular Localization: Secreted , Nucleus envelope

Poids moléculaire: 31 kDa

ID gène: 1773

UniProt: P24855