SUCLA2 anticorps

N° du produit ABIN2856701

L’anticorps Lapin Polyclonal anti-SUCLA2 a été validé pour WB, ICC, IF et IHC (p). Il convient pour détecter SUCLA2 dans des échantillons de Humain.

Aperçu rapide pour SUCLA2 anticorps (ABIN2856701)

Antigène: SUCLA2 (Succinate-CoA Ligase, ADP-Forming, beta Subunit (SUCLA2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SUCLA2 est non-conjugé

Application: Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Classe de qualité: KO Validated

Détail du produit anti-SUCLA2 anticorps

Réactivité croisée: Humain, Souris

Attributs du produit: Rabbit Polyclonal antibody to SUCLA2 (succinate-CoA ligase, ADP-forming, beta subunit)
SUCLA2 antibody [N2C3]

Purification: Purified by antigen-affinity chromatography.

Immunogène: Recombinant protein encompassing a sequence within the center region of human SUCLA2. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Commentaires:

Positive Control: Mouse brain , HepG2 , Molt-4 , HeLa

Validation: KO/KD

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Détails sur SUCLA2

Antigène: SUCLA2 (Succinate-CoA Ligase, ADP-Forming, beta Subunit (SUCLA2))

Autre désignation: succinate-CoA ligase ADP-forming beta subunit

Sujet: Succinyl-CoA synthetase (SCS) is a mitochondrial matrix enzyme that acts as a heterodimer, being composed of an invariant alpha subunit and a substrate-specific beta subunit. The protein encoded by this gene is an ATP-specific SCS beta subunit that dimerizes with the SCS alpha subunit to form SCS-A, an essential component of the tricarboxylic acid cycle. SCS-A hydrolyzes ATP to convert succinate to succinyl-CoA. Defects in this gene are a cause of myopathic mitochondrial DNA depletion syndrome. A pseudogene of this gene has been found on chromosome 6.

Cellular Localization: Mitochondrion

Poids moléculaire: 50 kDa

ID gène: 8803

UniProt: Q9P2R7