TUBA1A anticorps

N° du produit ABIN2856707

L’anticorps Lapin Polyclonal anti-TUBA1A a été validé pour WB, IF, IHC (p) et ICC. Il convient pour détecter TUBA1A dans des échantillons de Humain. Il y a 1 publication disponible.

Aperçu rapide pour TUBA1A anticorps (ABIN2856707)

Antigène: TUBA1A (Tuba1a) (Tubulin, alpha 1a (Tuba1a))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TUBA1A est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Détail du produit anti-TUBA1A anticorps

Réactivité croisée: Drosophila melanogaster, Humain, Souris, Rat

Attributs du produit: Rabbit Polyclonal antibody to alpha Tubulin 1A (tubulin, alpha 1a)
alpha Tubulin 1A antibody

Purification: Purified by antigen-affinity chromatography.

Immunogène: Recombinant protein encompassing a sequence within the center region of human alpha Tubulin 1A. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:20000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Commentaires:

Positive Control: NIH-3T3 , mouse brain , Jurkat , Raji , 293T , A431 , HeLa , HepG2 , H1299 , HCT116 , MCF-7 , NT2D1 , PC-3 , U87-MG , rat brain

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.73 mg/mL

Buffer: 1XPBS pH 7, 20 % Glycerol, 0.025 % ProClin 300

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Références pour anticorps anti-TUBA1A (ABIN2856707)

Chiu, Wen, Wang, Hsu, Tsai, Hung, Tseng, Shyr: "Role of estrogen receptors and Src signaling in mechanisms of bone metastasis by estrogen receptor positive breast cancers." dans: Journal of translational medicine, Vol. 15, Issue 1, pp. 97, (2018) (PubMed).

Détails sur TUBA1A

Antigène: TUBA1A (Tuba1a) (Tubulin, alpha 1a (Tuba1a))

Autre désignation: tubulin alpha 1a

Sujet: Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulins. The genes encoding these microtubule constituents belong to the tubulin superfamily, which is composed of six distinct families. Genes from the alpha, beta and gamma tubulin families are found in all eukaryotes. The alpha and beta tubulins represent the major components of microtubules, while gamma tubulin plays a critical role in the nucleation of microtubule assembly. There are multiple alpha and beta tubulin genes, which are highly conserved among species. This gene encodes alpha tubulin and is highly similar to mouse and rat Tuba1 gene. Northern blotting studies have shown that the gene expression is predominantly found in morphologically differentiated neurologic cells. This gene is one of three alpha-tubulin genes in a cluster on chromosome 12q.

Poids moléculaire: 50 kDa

ID gène: 7846

UniProt: Q71U36

Pathways: Dynamique des Microtubules, M Phase