FIG4 anticorps (Center)

N° du produit ABIN2856730

Cet anticorps Lapin Polyclonal détecte spécifiquement FIG4 dans WB, IHC (p), ICC et IF. Il présente une réactivité envers Humain.

Aperçu rapide pour FIG4 anticorps (Center) (ABIN2856730)

Antigène: FIG4 (FIG4 Homolog, SAC1 Lipid Phosphatase Domain Containing (FIG4))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FIG4 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunofluorescence (IF)

Détail du produit anti-FIG4 anticorps

Épitope: Center

Réactivité croisée: Chimpanzé

Réactivité croisée (Details): Chimpanzee (100 %)

Attributs du produit: Rabbit Polyclonal antibody to FIG4 (FIG4 homolog, SAC1 lipid phosphatase domain containing (S. cerevisiae))
FIG4 antibody

Purification: Purified by antigen-affinity chromatography.

Immunogène: Recombinant protein encompassing a sequence within the center region of human FIG4. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: Suggested dilution Reference ICC/IF 1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*

Commentaires:

Positive Control: HeLa , HCT116

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Détails sur FIG4

Antigène: FIG4 (FIG4 Homolog, SAC1 Lipid Phosphatase Domain Containing (FIG4))

Autre désignation: FIG4

Sujet: The protein encoded by this gene belongs to the SAC domain-containing protein gene family. The SAC domain, approximately 400 amino acids in length and consisting of seven conserved motifs, has been shown to possess phosphoinositide phosphatase activity. The yeast homolog, Sac1p, is involved in the regulation of various phosphoinositides, and affects diverse cellular functions such as actin cytoskeleton organization, Golgi function, and maintenance of vacuole morphology. Membrane-bound phosphoinositides function as signaling molecules and play a key role in vesicle trafficking in eukaryotic cells. Mutations in this gene have been associated with Charcot-Marie-Tooth disease, type 4J.

Cellular Localization: Endosome membrane

Poids moléculaire: 104 kDa

ID gène: 9896

Pathways: Inositol Metabolic Process