Fatty Acid Synthase anticorps (N-Term)

N° du produit ABIN2856754

Détail du produit anti-Fatty Acid Synthase anticorps

Antigène: Fatty Acid Synthase (FASN)

Épitope: N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Fatty Acid Synthase est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Réactivité croisée: Humain, Souris

Attributs du produit: Rabbit Polyclonal antibody to Fatty Acid Synthase (fatty acid synthase)
Fatty Acid Synthase antibody [N1N2], N-term

Purification: Purified by antigen-affinity chromatography.

Classe de qualité: KO Validated

Immunogène: Recombinant protein encompassing a sequence within the N-terminus region of human Fatty Acid Synthase. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Commentaires:

Positive Control: Molt-4 , 293T , A431 , HeLa , HepG2

Validation: KO/KD, Orthogonal

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Détails sur Fatty Acid Synthase

Antigène: Fatty Acid Synthase (FASN)

Autre désignation: fatty acid synthase (FASN Produits)

Synonymes: anticorps FAS, anticorps OA-519, anticorps SDR27X1, anticorps FASN, anticorps fj34h12, anticorps wu:fj34h12, anticorps Cgl0836, anticorps A630082H08Rik, anticorps BcDNA:GH07626, anticorps BcDNA:gh07626, anticorps DM_7295848, anticorps Dmel\\CG3523, anticorps Fatty acid synthase, anticorps anon-EST:Posey235, anticorps anon-EST:Posey43, anticorps anon-WO0138581.1, anticorps dFAS, anticorps fas, anticorps fatty acid synthase, anticorps fatty acid synthase Fas, anticorps type I polyketide synthase, anticorps Fatty acid synthase Fas, anticorps Fatty Acid SyNthase, anticorps fatty-acid synthase, anticorps fatty-acid synthase II, anticorps fatty-acid synthase fas, anticorps Fatty acid synthase 1, anticorps FASN, anticorps fas, anticorps Fasn, anticorps BAD_RS01360, anticorps fasn, anticorps fasn-1, anticorps NCgl0802, anticorps fasB, anticorps MT2600, anticorps TBMG_01448, anticorps FASN1

Sujet: The enzyme encoded by this gene is a multifunctional protein. Its main function is to catalyze the synthesis of palmitate from acetyl-CoA and malonyl-CoA, in the presence of NADPH, into long-chain saturated fatty acids. In some cancer cell lines, this protein has been found to be fused with estrogen receptor-alpha (ER-alpha), in which the N-terminus of FAS is fused in-frame with the C-terminus of ER-alpha.

Cellular Localization: Cytoplasm , Melanosome

Poids moléculaire: 273 kDa

ID gène: 2194

UniProt: P49327

Pathways: AMPK Signaling