CS anticorps

N° du produit ABIN2856769

Cet anticorps Lapin Polyclonal détecte spécifiquement CS dans WB, IP, ICC, IF, IHC (p) et IHC (wm). Il présente une réactivité envers Humain et a été mentionné dans 5+ publications.

Aperçu rapide pour CS anticorps (ABIN2856769)

Antigène: CS (Citrate Synthase (CS))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CS est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Whole Mount) (IHC (wm))

Classe de qualité: KO Validated

Détail du produit anti-CS anticorps

Réactivité croisée: Poulet, Grenouille, Humain, Singe, Souris, Rat, Poisson zèbre (Danio rerio)

Attributs du produit: Rabbit Polyclonal antibody to Citrate synthetase (citrate synthase)
Citrate synthetase antibody [N2C3]

Purification: Purified by antigen-affinity chromatography.

Immunogène: Recombinant protein encompassing a sequence within the center region of human Citrate synthetase. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Commentaires:

Positive Control: mouse brain , rat brain , Rat muscle , 293T

Validation: KO/KD

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.65 mg/mL

Buffer: 1XPBS pH 7, 20 % Glycerol, 0.025 % ProClin 300

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Références pour anticorps anti-CS (ABIN2856769)

Ding, Rose, Sun, Wu, Chen, Lin, Yang, Chen, Lee, Xu, Tian, Akinwuntan, Zhao, Guan, Zhou, Chi: "MESH1 is a cytosolic NADPH phosphatase that regulates ferroptosis." dans: Nature metabolism, Vol. 2, Issue 3, pp. 270-277, (2020) (PubMed).

Leandro, Violante, Argmann, Hagen, Dodatko, Bender, Zhang, Williams, Bachmann, Auwerx, Yu, Houten: "Mild inborn errors of metabolism in commonly used inbred mouse strains." dans: Molecular genetics and metabolism, Vol. 126, Issue 4, pp. 388-396, (2019) (PubMed).

Kim, Men, Liang, Receno, Brutsaert, Korol, Heffernan, DeRuisseau: "Effects of long-term exposures to low iron and branched-chain amino acid containing diets on aging skeletal muscle of Fisher 344 × Brown Norway rats." dans: Applied physiology, nutrition, and metabolism = Physiologie appliquée, nutrition et métabolisme, Vol. 43, Issue 2, pp. 165-173, (2018) (PubMed).

Nam, Akie, Sanosaka, Craige, Kant, Keaney, Cooper: "Mitochondrial retrograde signaling connects respiratory capacity to thermogenic gene expression." dans: Scientific reports, Vol. 7, Issue 1, pp. 2013, (2018) (PubMed).

Chang, Ulrich, Suliman, Piantadosi: "Redox regulation of mitophagy in the lung during murine Staphylococcus aureus sepsis." dans: Free radical biology & medicine, Vol. 78, pp. 179-89, (2015) (PubMed).

Détails sur CS

Antigène: CS (Citrate Synthase (CS))

Autre désignation: citrate synthase

Sujet: The protein encoded by this gene is a Krebs tricarboxylic acid cycle enzyme that catalyzes the synthesis of citrate from oxaloacetate and acetyl coenzyme A. The enzyme is found in nearly all cells capable of oxidative metablism. This protein is nuclear encoded and transported into the mitochondrial matrix, where the mature form is found.

Cellular Localization: Mitochondrion matrix

Poids moléculaire: 52 kDa

ID gène: 1431

UniProt: O75390