MAPKSP1 anticorps

N° du produit ABIN2856785

L’anticorps anti-MAPKSP1 Polyclonal produit chez le Lapin a été validé pour WB et IHC (p). Il convient pour la détection de MAPKSP1 dans des échantillons provenant de Humain. }

Aperçu rapide pour MAPKSP1 anticorps (ABIN2856785)

Antigène: MAPKSP1 (Mitogen-Activated Protein Kinase Kinase 1 Interacting Protein 1 (MAPKSP1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MAPKSP1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-MAPKSP1 anticorps

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Rabbit Polyclonal antibody to MP1 (MAPK scaffold protein 1)
MP1 antibody [N1C3]

Purification: Purified by antigen-affinity chromatography.

Immunogène: Full length human MP1 Recombinant protein.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Commentaires:

Positive Control: 293T , Rat2 , Neuro2A , Raw264.7 , C2C12

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.88 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Détails sur MAPKSP1

Antigène: MAPKSP1 (Mitogen-Activated Protein Kinase Kinase 1 Interacting Protein 1 (MAPKSP1))

Autre désignation: late endosomal/lysosomal adaptor, MAPK and MTOR activator 3

Sujet: This gene encodes a scaffold protein that functions in the extracellular signal-regulated kinase (ERK) cascade. The protein is localized to late endosomes by the mitogen-activated protein-binding protein-interacting protein, and binds specifically to MAP kinase kinase MAP2K1/MEK1, MAP kinase MAPK3/ERK1, and MAP kinase MAPK1/ERK2. Studies of the orthologous gene in mouse indicate that it regulates late endosomal traffic and cell proliferation. Multiple transcript variants are expressed by this gene, but only one variant is thought to express a protein.

Poids moléculaire: 14 kDa

ID gène: 8649

UniProt: Q9UHA4

Pathways: Signalisation PI3K-Akt